Articles

Metformin (Glucophage) for Weight Loss and Bodybuilding

Metformin, sold under the trade name Glucophage, is used to treat diabetes, but several studies show that it also helps non-diabetics to lose weight by reducing hunger (1).

You may be overweight because your body makes too much insulin, especially if your store your fat primarily in your belly. When you eat, your blood sugar level rises. The higher it rises, the more insulin your pancreas releases. Insulin makes you fat by acting on your brain to make you hungry, your liver to manufacture fat, and the fat cells in your belly to fill with fat. So the treatment for this type of obesity is to avoid foods that cause the highest rise in blood sugar and to take medications that prevent your blood sugar levels from rising too high. Avoid bakery products, pastas and all foods made from flour, fruit juices and everything with added sugar. Eat fruits and root vegetables such as potatoes only with meals.

Isotonic drinks

There was a time when having a drink after a workout meant a beer at the club bar. Not any more. Even the humble glass of water from the gym cooler has fallen out of favour with fitness enthusiasts. These days, we are encouraged to down a bewildering array of products, from energy-replacing isotonic drink to zero-calorie flavoured water loaded with electrolytes (mineral salts) that help keep the body’s fluid levels in balance.

But does the average keep-fitter need to drink unnaturally coloured bottled drinks or mix their own potions from powder during and after their thrice-weekly turn in the gym? Last month, experts warned that thousands of gym-goers were not only wasting their money on energy sports drinks, they were expanding their waistlines, too: as many of these drinks are full of calories, the report concluded that you would actually have to train even longer or harder to prevent the excess energy from the drink itself being stored as fat.

GW 1516 is often used in a "synergistic" combo with Aicar. Is it worth anything for bodybuilders. What do the analyses of black market analyses say. These chemicals are yet very hot and many "research chemicals" rave about it on forums (often as the sponsor). But is a fat or does it contribute to our chemical toolbox?

GW-1516 (also known as GW-501,516,GW501516 or GSK-516) is a PPAR 948; modulator compound being investigated for drug use by GlaxoSmithKline.[1][2] It activates the same pathways activated through exercise, including PPAR 948; and AMP-activated protein kinase. It is being investigated as a potential treatment for obesity, diabetes, dyslipidemia and cardiovascular disease. [3] [4] GW-501516 has a synergistic effect when combined with AICAR: the combination has been shown to significantly increase exercise endurance in animal studies more than either compound alone. [5][6]

GW-50156 regulates fat burning through a number of widespread mechanisms [7]; it increases glucose uptake in skeletal muscle tissue and increases muscle gene expression, especially genes involved in preferential lipid utilization.,[8][9] [10] This shift changes the body's metabolism to favor burning fat for energy instead of carbohydrates or muscle protein, potentially allowing clinical application for obese patients to lose fat effectively without experiencing muscle catabolism or the effects and satiety issues associated with low blood sugar. [11] GW-501516 also increases muscle mass, which improved glucose tolerance and reduced fat mass accumulation even in mice fed a very high fat diet, suggesting that GW-501516 may have a protective effect against obesity [12]

PRIMOBOLAN (Methenolone Enanthate)

If ever there was a steroid that can be considered “perfect” (or as perfect as can be), it would be Primobolan. It’s considered to be the safest and least suppressive anabolic steroid, has few side effects and is extremely effective. So why isn’t Primobolan used by everybody? The reasons may lie in many of the misconceptions surrounding this incredible drug.

Primobolan does not give fast gains, or more accurately, does not cause a quick increase in water retention, therefore it’s considered “weak”, yet in terms of building solid muscle, it’s one of the most effective steroids available. Because Primolan has little to no side-effects it is also used by older athletes and females. This also ruins its reputation amoung hardcore bodybuilders. Primobolan comes in a low dose mostly 100 mg/ml and isn’t cheap. It was also one of the most counterfeited steroids and then the active ingredient Was mostly a low dose of deca (around 20 mg/ml). This was also often the case with many UG products. And I always meet guys that honestly believe that the high dosages on the label compare to the real content. Primobolan is a very expensive compound to buy , the API (raw powder) costs around 14.000 euro. Even then you have to wonder what the quality of that API is. Luckely we have the ability to analyse. What also was feeding Primobolans bad reputation of being weak and expensive is the fact that (just like Growth Hormone) you have to use it for a considerable cycle length, 18 weeks at least and if possible even longer then 20 weeks. And at least 800 mg/week, because it is so mild you can easily use over 1 gram per week of it and not have any issues with bloating - destruction of your lipids - thicker blood etc.

The idea of steroids having direct fat burning properties is a commonly held belief among steroid users. This is why bodybuilders use steroids also during dieting, so they can maintain more muscle and lose more fat. How does anabolic steroids help burn fat, is it direct or indirect and what type of fat. I’ll help try to answer these questions.

Steroid fat loss studies

Unfortunately, most of the studies on fat loss and steroids is done on cattle. It’s a pretty scientific way of looking at it since it’s a controlled environment and they don’t do anything unique that might alter results.

In a study published in J Anim Sci. 2007 Feb;85(2):430-40 they measured carcasses of steers and cattle after they had been implanted with Synovex-Plus (SP), which is testosterone. This study shows that anabolic implants do not appear to have direct effects on intra-muscular lipid deposition. In other words implanting did not change the bodyfat percentage of visceral fat, the fat inside or around the muscles.

Another study J Anim Sci. 1999 May;77(5):1100-4 used implanted steroids trenbolone acetate plus estradiol benzoate ot progesterone at various times and dosages over 2 months. They found no significant differences on intramuscular lipid content.

Notice in those studies that they are talking about intramuscular fat. Its been theorized by many that steroids do a bad job of stopping intramuscular or “visceral fat”. However, they do seem to help promote fat loss overall. This is done by losing fat subcutaneously, which is the fat under the skin, which you can visually see.

A study published in J Anim Sci. 1996 Aug;74(8):1770-6. compared control cattle to three other groups; those implanted with trenbalone acetate, implanted with testosterone propionate +20 mg of estradiol benzoate, or both implants. This study found that groups all gained weight and lost fat(were leaner cows). Interesting enough they found the cows that had been implanted with 200 mg trenbolone acetate only, were the leanest.

Mestanolone (STS646 )

Methyldihydrotestosterone (methyl-DHT; 17alpha-methyl-17beta-hydroxy 5alpha-androstane-3-on (mestanolone) is a steroid that has characteristics similar to those of DHT (dihydrotestosterone), but unlike DHT is orally bioavailable [1]. Methyl-DHT was the second most commonly used steroid by German athletes in decades past, who were among the best in the world largely because of widespread steroid use [2]. There is comparatively little information, either scientific or anecdotal, on methyl-DHT, although there is a wealth of information on DHT. This article will discuss the information on methyl-DHT and what can be expected from this compound.

One common way of characterizing steroids is by their relative anabolic (muscle-building) and androgenic effects. Androgenic effects refer primarily to secondary sex characteristics: increased body hair, deeper voice, balding, and so on. Androgenic compounds characteristically also have strong psychological effects, such as increased aggressiveness and concentration. Among bodybuilders, highly androgenic compounds are commonly used pre-contest or during cutting cycles for increasing muscle hardness and decreasing water retention and also to provide stimulation and increase concentration and performance in the gym. They also typically have anti-estrogenic effects.

The anabolic and androgenic effects of methyl-DHT were compared to testosterone and methyltestosterone in some early animal studies [1]. In tests of its androgenic potency (total of five tests), methyl-DHT ranged from 20-255% as androgenic as testosterone or testosterone propionate, with a per study average of 70%. In terms of anabolic effects relative to testosterone, the range was 25-105% with an average at 55%. One study also compared the effects of methyl-DHT to methyltestosterone, and it measured as ~60% as androgenic and 25% as anabolic. The large differences in these values are due to multiple differences in experimental design, not to mention the problems with extrapolating animal research to humans, but this research does give a general idea of what the potency and effects of this compound might be.

Clenbuterol.. Hard Core Bodybuilding done safe

Clenbuterol is a very potent compound it works in micrograms (1/1000th of a gram). Therefore it’s very hard to dose it correctly. Many Underground Labs have inconsistent dosing. The label claims 20 mcg per tablet, but some tablets contain almost nothing while others are too high dosed. Some Chinese compounders ‘ solved” that problem by overdosing their tabs resulting in unwanted visits at the emergency room in the hospital. Production of tablets and API (raw powder) of Clenbuterol is no longer allowed in China since  September 2012.

In the last few years Clenbuterol (clenbuterol hydrochloride) has replaced Ephedrine HCL (hydrochloride)  as the drug of choice when it comes to fat loss and contest preparation in general. Clenbuterol is used throughout the world as a bronchodilator for asthma patients. In terms of fat loss, ‘Clen' (as it's frequently called) is what's known as a "repartitioning agent" - an agent that increases your ratio of lean muscle mass to fat mass.
 

Hollywood’s Secret Skinny Pill –

This is one of the most informative and controversial articles you’ll ever read about Clenbuterol and its  ability to induce rapid weight loss.

Hence the warning: Clenbuterol is illegal and potentially very dangerous for humans. We, here at Juicedmuscle, in no way, shape, or form, endorse its use.

The information presented here is strictly for educational purposes only and is not intended to replace the advice or attention of healthcare professionals.

Every generation of print media, television and motion pictures holds several examples of celebrities who were or are overly susceptible to the pressures to be thin.

Add to that the number of female athletes forced to strip away all body fat, the innumerable multitudes of common people subjected to abuse or scorn based on society’s fickle standards, and individuals suffering from eating disorders and unhealthy compulsions and it’s easy to understand why there’s such a huge demand for powerful weight-loss drugs.

This first article on Clenbuterol is on use by women, the next one will be on Clenbuterol use for Bodybuilders.

Posting about women gives me the oppurtunity to post a picture of this incredible hot chick!!

Peptide Guide :

1 - You are on this site because you have heard of and want to become more familiar with Growth Hormone Releasing Peptide (GHRP) and/or Growth Hormone Releasing Hormone (GHRH). These 2 materials administered can give you an increased quality of life in ways of anti-aging, muscular hypertrophy, fat loss, injury repair, higher bone density, and better sleep.

2 - GHRP can be used on its own to increase our natural Growth Hormone (GH) pulse release from the Pituitary Gland in the brain. GHRP dosed in conjunction with GHRH will amplify our growth hormone release significantly to gain maximal benefit.

3 - There are various types of GHRH's. The only GHRH to consider is tetra-substituted CJC-1295 / CJC-1295(without DAC) / modGRF(1-29). They are all the same thing but with a different name. They come in vials ranging in material weights measured in milligrams (mg) consisting of a solid freeze-dried (lyophilized) substance.

4 - There are various types of GHRP's. GHRP-6, GHRP-2, Hexarelin, and Imaporelin. The differences between them are potency and side effects. GHRP-6 is very potent and makes you quite hungry. GHRP-2 is potent and can slightly affect your sleep somewhat. Hexarelin is very potent but you can desensitize from higher dosages. Imaporelin is potent with the minimalist side effects of all 4 GHRP's.

5 - Peptides are dosed via a regular 1mL needle syringe typical to what a diabetic would use. It is administered Subcutaneously (SubQ) (just under the skin into the fat tissue), most usually around the abdomen region.

6 - The required amount (saturation dose) is 1mcg (microgram) per Kg (Kilogram) of bodyweight. The typical usage and for ease of measuring is 100mcg of modGRF(1-29) and/or 100mcg of your choice of GHRP. Lower dosages will simply result in less GH release due to a slightly weaker GH pulse and reduce any side effects you may have. A higher dose will have minimal benefit and is more a waste of money than anything else. But, in saying that, the more frequently dosed in any given day would result in more frequent pulses.

Thymosin beta 4 ( akaTB500)

Bodybuilders once started to use Boldenone and Trenbolone which was meant for cattle to beef up. Als many vitamin preparations where used from France. Now a new and exiting veterinary peptide emerged. Now available  with an acetate estrification for use in humans.  It seems to help after hairloss too. It was first used in horses but now the first bodybuilders start to use it.  Now I hear more and more that top athletes try this new peptide.

TB-500 or Thymosin Beta 4, as it is called, is a exploration peptide that is tested primarily for its abilities to increase strength, endurance and restoration in subjects. It is often used in horses in the course of clinical trials and is sold for study purposes only. It is known to have many of the same effects of growth hormone in animals equating to results in humans that would be related to an increase in testosterone Inspite of. It has been shown to inhibit tumor growth making TB-500 a amazing product for research studies and with further testing, something that may become widely accepted in the minds of many.