Real / Fake

Most of the anabolic steroid not only dock to the androgen receptor, but also to the receptors for estradiol and progesterone. Knowledge about that is also relevant to steroids users, because the progestogenic and estrogenic effect of steroids tells us something about their possible side effects. In 2009 some Dutch researchers published a survey which might benefit health conscious steroids users.

The more you know about anabolic steroids, they more complex they seem to be.  If you start to study the chemistry of anabolic steroids you start to understand how various modifications are meant to prevent the conversion of steroids into estradiol-like and DHT-like hormones, while at the same time allowing for an increased anabolic effect. But if you understand that, you'll discover that it all works just a bit more complicated.

When we wrote the Underground Book Thailand had closed his borders for Steroids and Male enhancement pills, mostly counterfeited Viagra. Pfizer makes millions of profit, producing a sildenafil containing tablet costs only cents and they sold it for a hundred fold. Thailand also sold cheap generic tablets and many people where able to buy outside their regional healthsystem. We all know how strong the pharmaceutical lobby is. The uSA protects his taxpayers and the pressure on Thailand became so high that it gave in.

China in fact owns the USA (financially) and this proud country didn’t gave in, the bodybuilding community had acces to China’s big pharma. First they sold reliable Growth hormones (rhGH) the famous Jintropin and ruined the very high prices of the US and European Pharma’s asked for their products. China also sold cheap API’s (raw powders) and all the necessary ancillairies. Soon all kind of Underground Laboratories (UG Labs) some good most of them bad, and home brewers bought their products in China.

The research towards the myostatin inhibitor ACE-031 was terminated - but it does work

The pharma companies Acceleron Pharma and Shire have put the myostatin inhibiter ACE-031 on ice. That have indicated. [Acceleronpharma.com May 2, 2013] And that's pretty weird. Them in a joint press release a few days ago

A few weeks earlier, Muscle & Nerve published a study showing that ACE-031 is a compound which a chemical bodybuilder would gladly add to his toolbox.

The injectable ACE-031  is a synthetic activin receptor type IIB. Muscle cells have that receptor too. It is intended for proteins as myostatin, GDF11 and activin A and B. If myostatin docks itself to the activin receptor type IIB, then the growth of muscle fibers reduces. Under the 'right' circumstances myostatin even breaks down muscle.

If you inject ACE-031, then that does not happen. The synthetical activin receptor type IIB captures the muscle inhibitory proteins away, and disable them.

 

Johnson tested positive for stanozolol (winstrol) metabolites after he won the 100 meter finals over long-time rival Carl Lewis at the 1988 Seoul Olympics. For many years people guessed why and how a top athlete and the world's fastest man, surrounded by a knowlegable trainer/coach (Charlie Francis) and a knowledgable doctor (Dr. Jamie Astaphan) could have been cought for the use of performance enhancing drugs. Now we could get the complete picture, based on a few reliable sources, such as:

Johnson’s  comments during an interview with journalist and author Richard Moore. Moore’s book, “The Dirtiest Race in History: Ben Johnson, Carl Lewis and the Seoul Olympic 100m final”  both from  June, 2012. Ben Johnson’s secrets from the book “Speed Trap”, written by Charlie Francis( Ben Johnson track coach) and testomony before the Canadian Government inquiry into the use of performance-enhancing drugs by athletes like Angella Issajenko. All parts posted below.

Doping in Sports

Almost seven years after police discovered hundreds of bags of blood in a Madrid clinic during the Operacion Puerto doping investigation, Dr Eufemiano Fuentes and five others will finally go on trial, starting January 28, 2013.

Doping was not a crime in Spain at the time of the raids and so the Puerto six have been accused of crimes against public health.

Dr Fuentes himself confirmed in the media that he had worked with athletes from several sports, including tennis, athletics, boxing, football as well as cyclists. Officially closed in September 2008, Operación Puerto has been said to involve more than 200 athletes, but only  some 50 cyclists have been named as clients. It is realistic to think that other names will be named during this trial.

All this has come about from "Operation Greyhound" (Operacion Galgo) in 2009, which is the second high-profile organized effort against doping in Spain involving Fuentes. The first was Operation Mountain Pass (Operacion Puerto) in 2006, which was mostly known for having caught out a few high-profile cyclists for doping with Fuentes' aid. Now in Januari 2013 the police arrested the former cyclist José Luis Martínez for allegedly trafficking in banned performance-enhancing substances, police said that they had found more than 300,000 doses of banned substances in a secret laboratory in the southeastern town of Molina de Segura. Substances included clenbuterol, primobolan, testovis, testosterone, proviron, growth hormones, ephedrine.  This case  is linked to both major doping operations mentioned before.

Fuentes made the claim that other sports besides cycling were involved. Operation Greyhound has already shown this to be the case with the World Champ Steeplechase runner Marta Dominguez being suspended. Fuentes' statement, which implies that doping was done by the Spanish national fottbal team, could hold some truth for sure. Not just with that team but other footballers and professionals from various sports (a cyclist called Manzano claimed during the time of Operacion Puerto that he saw footballers and tennis players at the clinic).

In the media we have seen numerous articles about cyclists and cycling. We as juicers know that almost every athlete on the Olympics etc etc uses banned substances. Shooters using beta-blockers. Cycling is used as a scape goat, but during the Olympics in Australia I saw swimmers sooo obvious on growth hormones.

Its time we face the truth, there is no such thing as a “clean” sport not with all that money involved. And even before that, people will do anything to win, just google.

We as bodybuilders know that pro-bodybuilders use AAS, but an enormous amount of “cosmetic “ users also take these means. Just google the historical timeline on spots doping. Its as old as competitive sport itself.

Metribolone-Methyltrienolone-R1881

On the left you see a picture of ampoulle made by Newgenpharm, Korea. Its an obvious fake, seen the doses.

Metribolone is an extremely powerfull steroid, some experts even call it monstreous. It is hard ro buy the real products and API's. Mostly because its not only extremely potent, but also extremely expensive. Underground manufacturers that don't have direct contact with an manufacturer of these powders and don't have the ability to analyse them will end up with a substitution or a very underdosed product. We all seen that during our analyses and everyone elso know this from the market in recreational drugs. Most recreational drugs (cocaine or speed by example) are cut heavily, because everyone involved wants to make a profit. Believe me there is no difference in Anabolic market.

Underground Labs (UG) now sell this product as designer steroid and also a mixed product (Hard Core Labs MT-DMN) more info at the end of the article.

You see in increasing amount of both orals (sold as Oral Tren or Oral Parabolan) aswel as injectables. Scientific research showed that subQ injected "oral steroids"  where a minimum tenfold more potent then the oral version.

On the rigt you see a picture with UG Labs selling more realistic dosed products. Geneza Pharma with 250mcg/tab. Genpharm with 10 mg/ml and DutchLabs with 2 mg/ml

In the area of pro-hormones there was a methyldienolone product on the supplement market. That of course disapeared with all other pro-hormones.

 Methyltrienolone is essentially the same compound as trenbolone that has gone under 17 alpha alkylation so that it can remain active after oral administration. So in a basic sense, methyltrienolone offers all of the advantages of trenbolone with the added bonus of being orally active. However, that extra benefit comes with a hefty price when it comes to hepatoxicity as will be demonstrated below.

Methandriol Dipropionate

Substance: methylandrostenediol dipropionate

This compound was first manufactured in the early 80’s as an oral tablet, it also comes as an injectable, dragees which are intended for subglossal intake ( Novandrol from Galenika) and as a water dissolved compound (Methyldiol Aqueous).It was widely used by strongman, powerlifters, bodybuilders and lets not forget other bulk users such as wrestlers and foot ballplayers. Even here, users found out that it was beneficial to combine the oral MD with other steroids. After  a short period other compounds became more popular and MD seemed to be forgotten. But not in Australia and New Zealand where a lot of veterinary steroids like: Androbol® Denkadiol® Drive® Filybol® Filydoc® Geldabol® Libriol® Metabolin® Methandriol® Metasus® Nandrobolin® Protabol® Spectriol® Superbolin® Tribolin “75” ®, used for animal vetting, contained this magical component. Its purpose here was weight and mass gain. It was very popular in Australia and New Zealand because it was much more easily procured than anabolic/androgenic compounds for human use. Some users claim that MD actually increases cell receptor stimulation, and sensitising  the androgenic receptors of the muscle cell  and cause other steroids to work better at the site of cell binding. Others claim that it “cleans” the steroid receptors, wich of course is impossible, no such mechanism is known, what it does do is bind very tightly to the steroid binding globules in the blood stream, displacing other, more effective, in the stack added steroids, and possible amplifying them. That is probably why it's included. in some form, in a lot of combination drugs. That is not to say that it is a weak steroid on its own. It certainly is not. Methandriol on itself is a high anabolic, high androgenic steroid. It is used for strength and weight gains. On its own it is highly estrogenic, wich means that it doesn’t need the enzyme aromatase to convert to oestrogen, but it is estrogenic by nature. In a stack or combined steroid cocktail it is only moderate estrogenic. But it is still not very popular on its own. Most products contain methandriol dipropionate in a combined cocktail, only Denkall Mexicana, a vendor of Troy Laboratories from Australia, sells  a product that contains only methandriol dipropionate 75mg/ml. This gave US athletes the opportunity to create their own magic. Athletes predisposed to gyno could consider to add Proviron® or Clomid® to their stack as a estrogen blocker. Some lifters feel it works well stacked with injectable testosterones. Actual visible side effects are mild in this drug. The injectable form is only slightly toxic. The most common side effects come from the androgenic portion of the drug and can produce mild acne, oily skin, body and facial hair growth as well as hair loss and high blood pressure. Some report gastrointestinal stress. Overall it's a pretty clean drug in the side effect department.

Understanding Esters, Steroid Active-Life and Half-Life

 

First all these numbers and calculations are debatable. Scientific research showed that all numbers are influenced by the injection spot (shoulder or butt Organon) the depot volume (same research). Ciba showed that your metabolism rate is also very important how much active ingredients is used or excreted, if you use T3 your excretion increases, probably the same is true for ephedrine, coffein, clenbuterol etc. Swedish research showed that the carrier, solvent, co-solvent etc is from major importance. The Nebido research confirmed this. Read more here:

//juicedmuscle.com/showthread.php?353-Active-Half-Life-of-Steroids

Anyone new to steroids may be wondering what this means, even some experienced steroid users may also be wondering what this means. So here in simple terms you can read and hopefully understand all about steroid half life's and what this term means.

Basically every drug has a half life, steroids included. If for example, you were to inject 1000mg of testosterone cypionate once weekly, for 10 weeks, how would you know when you were "off"? Would you be "off" when you had finished your last dose? You would be able to calculate this from the half life of testosterone cypionate . The half life of testosterone cypionate is around 12 days. This means that 12 days from your last shot of 1000mg of testosterone cypionate (Time to start PCT ? You decide.), your blood levels of testosterone cypionate will contain 500mg of the steroid . Another 12 days from then, i.e. 24 days from last dose, your blood levels will contain 250mg of the steroid . This amount then keeps halving every 12 days. At 48 days (almost 2 months) from your last dose, your blood levels will still contain 67.5mg of testosterone cypionate .

GHB

GHB are the abbrivations of Gamma Hydroxy Butryaat, also called ”Liquid XTC” or just “X”. But GHB has nothing to do with XTC. Initially the drug was developed as an anestheticum in 1960. The use as a narcosis means has strongly been decreased in the meanwhile, because there are many better resources at the present time. Also the substance was used as a means against insomnia or other sleepimpairments, as appliances at labour and to treat alcoholic abstention phenomena. In animal experimentings GHB had shown to be involveded in the production of Growth Hormone, and that their levels increased during administration, and this draw attention of bodybuilders. Allready soon it became the nickname “growth hormone booster”. Until now no scientific proof has been delivered that GHB raises growth hormone levels in human beings, nor that it prevents the muscle tissue breakdown. During the eighties and nineties GHB became popular at bodybuilders. GHB was a widely available over the counter supplement  until it was banned by the US FDA in 1990. The substance has many beneficial effects, but it was typical used by bodybuilders and athletes because it can significantly raise growth hormone levels. Unfortunately, the increase in GH levels is also accompanied by an increase in levels of prolactin. The increase in prolactin counteracts many of the positive effects of an elevated GH level. This probably explains why many athletes experience, very little as far as muscle growth with the use of GHB. Several athletes using GHB, report an increase in lean body mass and strength increase. Many users don’t experience any muscle or strength increase, but do feel GHB helps to accelerate fat loss.

The Drug Life of a Pro Bodybuilder

Professional bodybuilders – NOT like you and me! That’s an understatement. But an even bigger understatement is that we clearly don’t take the same AS as pros; and certainly not in the same galvanic portions!
 Everything changes when a pro card passes from the IFBB to a national champion’s back pocket. The game is raised, and the expectations along with it, as well as how things work. That is to say, all of a sudden, your IFBB pro card fits in the magic card key slot, and the golden door of opportunity just opens up and welcomes you inside. “Inside”, being the inner sanctum of drug use that includes everything from price to availability to the means to acquire steroids and other useful substances. After all, AS cycles are the lifeblood of a pro’s career. Anyone who tells you differently, is deluding themselves, and trying to delude you. So just what kinds of drugs do pros take at that level of competition? We’ll get to that in a minute. Let’s first look at what it actually means to be a pro….

First, the moment an athlete turns pro at the USA or the Nationals, drug dealers all over town are scrambling to either keep or get New Pro Guy’s business. They know he’s going to be needing an incredible amount of drug supply on a regular basis with his new status, and that he’ll continue buying them for a long time if he’s a success up on the stage and doesn’t blow it with poor condition. They want to be his supplier for the long haul. Keep in mind that it’s a matter of prestige and legitimacy for a supplier, too:
 

If Regular Guys A & B, prospective new clients, need drugs, they’re going to go to that supplier because they know he supplies New Pro Guy. If it’s good enough for New Pro Guy, it’s certainly good for their cause, and it increases Drug Dealer’s client base and income.

The other benefit to turning pro, where acquisition is concerned, is simple: Many hangers-on, wannabes and entourage prospects, will want to acquire the drugs for a new pro, because they want to curry favor, and be N.P.G.’s buddy so they can say that they “know New Pro Guy”. Now he owes them, but he’s gotten to keep his nose clean. He no longer has to approach dealers himself, and risk a raid or arrest. Either they come to him, or he can send any number of willing guys to the dealer on his behalf.

Being a new pro means being catapulted to instant “Fuckable New Pro Guy”. Ahhhh, the allure of a laminated piece of paper, half the size of the palm of your right hand! As a new pro, there’ll be rarely a lonely night, and N.P.G. has an instant cook, laundress and steroid/ drug mule to do his bidding where once these filthy chores were his alone! This changes everything, believe it or not. Now he has more time to spend acquiring drugs, taking drugs, training, and finding other girls to keep on the side.