The research towards the myostatin inhibitor ACE-031 was terminated - but it does work
The pharma companies Acceleron Pharma and Shire have put the myostatin inhibiter ACE-031 on ice. That have indicated. [Acceleronpharma.com May 2, 2013] And that's pretty weird. Them in a joint press release a few days ago
A few weeks earlier, Muscle & Nerve published a study showing that ACE-031 is a compound which a chemical bodybuilder would gladly add to his toolbox.
The injectable ACE-031 is a synthetic activin receptor type IIB. Muscle cells have that receptor too. It is intended for proteins as myostatin, GDF11 and activin A and B. If myostatin docks itself to the activin receptor type IIB, then the growth of muscle fibers reduces. Under the 'right' circumstances myostatin even breaks down muscle.
If you inject ACE-031, then that does not happen. The synthetical activin receptor type IIB captures the muscle inhibitory proteins away, and disable them.
