Articles

SARMS ( Selective Androgen Receptor Modulators)

Submitted by RonnyT on Mon, 2014-12-08 10:50

Androgens are a class of hormones that serve as ligands that bind to cellular androgen receptors. The androgen receptor is involved in a complex signal transduction pathway that ultimately results in greater expression of specific genes.

All anabolic steroids and pro hormones offer their muscle building properties through this binding to the androgen receptor.

A drug that can either block or stimulate the same nuclear hormone receptor under different conditions is called a selective receptor modulator. If it can block or stimulate a receptor in a tissue selective manner, it may be able to mimic the beneficial effects in one tissue and, at the same time, minimize the unwanted effects of the natural or synthetic steroidal hormones in other tissues.

Desiccated Liver and Vitamin A

Submitted by RonnyT on Wed, 2014-11-26 14:13

The dense forest of bodybuilding nutrition contains a paradox: the quantity of information available is abundant, but the wisdom of traditional diets to satisfy the primary concerns of bodybuilders is sparse and hard to find. Typical recommendations include very low-fat diets rich in protein foods like salmon and chicken.

You will search in vain through mainstream men’s health magazines to find so much as a mention of the importance of vitamin A to bodybuilding. Yet this nutrient is essential to muscle-building and may be the bodybuilder’s most potent weapon. Vitamin A is necessary for the utilization of protein and the production of testosterone and other growth factors. In fact, one human study, discussed below, found the administration of vitamin A and iron to have results equivalent to the administration of testosterone itself. Rather than advocating the consumption of vitamin-A rich foods such as liver and natural food-based supplements such as cod liver oil, mainstream men’s health writers are advocating diets very high in protein, which deplete vitamin A reserves, leaving one to wonder whether the athletes who resort to over-the-counter steroid supplements might be able to achieve similar results by consuming a traditional diet, rich in vitamin A.

NEBIDO in Bodybuilding

Submitted by RonnyT on Thu, 2014-11-20 10:17

Something odd happened with Nibido. Bodybuilders always closely monitored scientific development on steroids. These researches are meant to treat diseases or meant to develop a male anti-conception compound. Especially means against male hypogonadism had our warm interest. Bodybuilders in the past always experimented with testosterone, methyl-testosteron, dianabol etc. The pharmaceutical companies worked hard on means that required less labor (read injections) from doctors or nurses. Compounds like cypionate and enanthate where frequently used, but their kinetics where undesirable because of the quick peaks and downs, it caused an emotional rollercoaster with moodswings, and libido that was extremely high followed be a sexual disinterest. Organon developed Sustanon a compound containing four different testosterone esters that in theory caused a more stable testosterone level.

Andriol Testocaps re-examined

Submitted by RonnyT on Wed, 2014-11-12 18:30

If someone asks a question on a bodybuilding discussion forum about Andriol (Testosterone Undecanoate) most of the time members chime in and answer the same stereotype answers that where valid some years ago. About Andriol being a poor choice due to poor absorption rate and therefore has a low bioavalability. It is expensive etc etc.

Testosterone undecanoate has been available on the market for more than 20 years. Andriol capsules are available in more than 80 countries worldwide, but not in the USA. This should actually show that it has much potential. Also for bodybuildersit has a lot of uses like in bridging, cycling, PCT, HRT/TRT, anti-aging etc. More of that later.

Given Testosterone Undecanoate’s “age,” there would be little financial incentive to market the drug in the United States, as any generic manufacturer (foreign or domestic) could introduce a cheaper version, negating any potential for profit. Thus, it is unlikely that Testosterone Undecanoate will enter the United States market in the near future.

EPO article

Submitted by RonnyT on Fri, 2014-11-07 10:02

EPO in Bodybuilding and Sport

Erythropoietin, also known as Epo, is a protein that is made by that kidney that stimulates the formation of red blood cells. Red blood cells carry oxygen in the blood and more red blood cells means better endurance performance.

Erythropoietin alpha is sold as Epogen and Procrit and a synthetic form called darbepoetin is sold as Aranesp. All of these products are produced in an injectable form. Aranesp is dosed weekly or every two weeks while Epogen is dosed three times per week.

Mircera is an artificial form of erythropoietin (EPO) stimulators similar to Amgen’s Epogen and Aranesp. But Mircera is thought to be superior to Epogen and Aranesp due to the use of pegylation technology that provides a sustained release of erythropoiesis stimulating proteins (ESPs). PEGylated erythropoietin (PEG-EPO) results when a molecule of polyethylene glycol is attached.

Tainted Nutraceuticals

Submitted by RonnyT on Wed, 2014-10-29 10:47

The global nutraceutical market was estimated to be $140.1 billion US dollars in 2010. Concerns have arisen over the increasing cases of adulterated products in the market which threaten the health of the consumer and the continual growth for the nutraceutical industry.

US rulings such as the 1994 Dietary Supplement Health and Education Act (DSHEA), the 2007 Good Manufacturing Practice of Dietary Rule and comparable rules from other countries have set guidelines to ensure product safety and manufacturing compliance.   outgoing raw materials and finished products The U.S. House of Representatives has passed legislation clamping down on designer steroids and pro-hormones and giving more powers to the DEA.

Glute Training

Submitted by RonnyT on Thu, 2014-10-23 11:20

I would like to start this article about the glutes with a picture and explanation about the pectoralis. Why, because most bodybuilders know more about their pecs then about their butt.

We are all born with a genitical determent body-type and all our muscles have a certain form. Of course we would all like to have the perfect form and body-type as well as a six-pack. Its only sad that most of us will have to work hard to get those hot desired full round muscles.

Chicken legs

Submitted by RonnyT on Thu, 2014-10-16 08:54

Almost everyone has a favorite muscle group they like to train and develop best. For most of the new or young builders this is the biceps/arms. Why is this, probably because strong arms and especially the flexed biceps is the summum of showing your strength. On the other hand, most people also have a muscle group they don’t like to train. And mostly that is legs.

Developing oak tree legs asks a lot of dedication and hard work. Training the legs wears you out and is often very painful, moreover most people don’t consider muscular legs as "sexy" as the biceps. They are often covered up and no eye catcher as fully pumped arms.

Back-loading syringes

Submitted by RonnyT on Tue, 2014-10-07 08:39

In the last decade the usage of growth hormone and IGF-LR3 became common among bodybuilders, anti-agers and fitness enthusiasts.

In the beginning people where cautious because they feared side-effects after continuous growth hormone use. And the price was very high also.

Nowadays we see that most discussion-boards have a peptide section. And it’s no longer restricted to GH and IGF. People that used the cadaver extracted GH, will tell you mixed GH is much more effective than the synthesized version. So people started to experiment with GH releasers aka secratogogues.

Research has overwhelming shown that when administering one GH peptide from each class in conjunction (GHRH + GHRP), a synergist effect is achieved, eliciting superior results compared to using just one alone. For this reason, it has been common practice to combine both a GHRH and a GHRP for years. This practice is well-founded, as it is backed not only by credible science, but by a massive amount of anecdotal evidence in terms of both personal experience and user blood work.

Because some bodybuilders wanted to mimic natural GH release they experiment with pulsing their dose in 2 or 3 injects per day. There are many different injection protocols with many different injection frequencies for GH releasers and combinations there off.

AGE’s - Aging and Bodybuilding

Submitted by RonnyT on Fri, 2014-10-03 08:43

Too many ages will make you fat. But the longer-term consequences are much more severe. A process starts in which “silent” inflammation occurs in different parts in your body. Your arteries get clogged, your brain deteriorates and your kidneys can’t do their job properly. If this process does not stop, you have a greater chance of getting Alzheimer's or on a premature death by heart and vascular disease.

First saturated fat was the main culprit in cancer and cardiovascular disease, but that was not true. Then we all went “low carb” because we became too heavy from all those unhealthy sugars and carbohydrates. And now that story can also be thrown into the trashcan?

 

Not really. Sugars and fast carbs are still not good, too much sugar (especially fructose) chases the spontaneous formation of AGE’s in your body