Yohimbe, found in the bark of the evergreen tree (pausinystalia johimbe) and is indigenous to central and western Africa. Its appearance is most prevalent in the Congo, Cameroon, Nigeria, and Gabon. It has gained much popularity, not only as a treatment for impotence, but also as an effective tool for decreasing body fat. In 1938, the principal alkaloid yohimbine was discovered to be the active component responsible for most of the effects of the yohimbe bark. This compound has now been isolated and is sold as both an aphrodisiac and fat loss aid. Although yohimbine is the most important constituent in yohimbe, it is likely that it contains 31 other yohimbine alkaloids that can be present in herbal yohimbe preparations. Some of these have different and unknown selectivity’s and potencies and effects, at the adrenergic receptors, in addition, these preparations vary greatly from brand to brand and even from batch to batch, as no standardization for extraction exists. In fact, an investigation found that most over the counter preparations have little to no actual yohimbine.