Methandriol Dipropionate

Methandriol is an anabolic steroid which is a derivative of the hormone dihydrotestosterone. Methandriol Dipropionate has an added propionate ester added which makes the drug active in the body for several days instead of the short period of time that the unesterfied preparation of this substance is also available in. Methandriol was first developed in the 1930’s, making it a very old agent as far as anabolic steroids are concerned. Methandriol was developed into a medication by the pharmaceutical company Organon, which sold it in the US under the Stenedriol brand name. When Organon was marketing this item, it was available in both oral and injectable forms. Many other manufacturers soon followed producing this drug and it became a widely popular anabolic steroid during the 1950s. Methandriol was essentially the first steroid perceived to have a notable separation of anabolic and androgenic effect, which was a persistent goal of pharmaceutical developers at the time. But it was later confirmed that the dosages needed to cause any tissue growth in humans would also cause androgenic side effects due to the week anabolic nature of this substance. Soon more effective anabolic preparations became available and Organon and the rest of the companies producing this drug discontinued its production. Now it’s only found in international markets, mainly Australia where it is marketed as a veterinary medicine.

Methandriol is known as a weak anabolic steroid with weak androgenic properties as well. It also displays some level of estrogenic activity meaning that this weak substance isn’t ideal for cutting like most other weak anabolics are used for. Because of this, the drug never gained much popularity amongst the bodybuilding community, although it was sometimes used in place of other agents in bulking stacks when available. While it may be possible to use methandriol alone for muscle building purposes, it is most often combined with Deca-Durabolin or Equipoise where measurable gains of hard muscle mass accompanied by a low level of water retention can be noticed. When looking for a more pronounced gain in mass, a stronger androgen like testosterone can be added. Methandriol is not directly aromatized by the body, but one of its metabolites is however. Because of this, methandriol is considered a mild to moderate estrogenic compound. Gynecomastia should only be a concern when running extremely high doses of the substance. However, other milder estrogen related side effects can become apparent during use. These side effects include water retention and increased fat retention as well. Methandriol is also androgenic in nature, meaning that androgenic side effects are possible when taking this drug. These side effects can include things such as oily skin, acne, and increased body and facial hair. In women, androgen can cause masculizing side effects such as clitoral enlargement, deepening of the voice, and facial hair growth. Like all other synthetic anabolic steroids, the use of methandriol will cause the body’s natural testosterone function to cease. To deal with this, users will want to run a post cycle therapy protocol upon discontinuing their cycle. Users often choose to use substances such as clomid and HCG to get their body’s natural function restored.

Early prescribing guidelines for methandriol recommend a dosage of 25mg a day given 2 to 5 times a per week. For bodybuilding and performance enhancing purposes, a typical dosage is in the range of 200-400mg per week with the injectable preparation of this steroid. Cycles generally last no more than 6-8 weeks in an effort to minimize hepatotoxicity and strain on the liver since this drug is a C-17aa. This level of use is sufficient for moderate gains in muscle size and strength, which may be accompanied by a low level of water retention.