Increased Estrogen

Increased T/E ratio in men

 

When testosterone levels are normal, and a man is experiencing signs of andropause, the hormonal culprit is usually estrogen (and chemicals that mimic the actions of estrogen), the female hormone. Both men and women have specific amounts of estrogen in their bodies. Young men may have a ratio of testosterone to estrogen of 50:1. The ratio drops to 20:1 or even as low as 8:1 with normal aging.

When estrogen levels in a man increase, the actions of testosterone are reduced. Even worse. While estrogens in women protect them from heart disease and osteoporosis, the effects are the opposite for men. Too much estrogen will actually increase the risk of heart attacks in men.

Unfortunately, this is exactly the set of problems that we are currently facing. A combina­tion of our lifestyle and dietary choices, stress, use of anabolic androgenic steroids, medications and/or alcohol coupled with the pervasive amounts of estrogenic pollutants found in plastics and our water supply are the reasons why estradiol levels are climbing in men. In fact, we now see men with estrogen levels higher than that of many women.  As estrogen rises in men, testosterone drop and mammary gland tissue begins to grow (creating male breasts). This problem is so common that male breast reduction is now the fastest growing surgery in America!

And it is this elevated estrogen level which will reduce the T/E ratio and reduce the critical anabolic to catabolic ratio.  An ideal testosterone to estradiol level is around 50:1. In assessing thousands of men via saliva testing, we find that less than 10% achieve these critical ratios and over 75% of them are less then 35 years old! 

Saliva testing is an excellent and cheap method to  test the important male hormones including estradiol, the most active form of estrogen. If testing shows that your estradiol levels are high and/or free testosterone levels are low or low normal.

How Does Estrogen Occur In A Man's Body? Within the body, there is an enzyme called aromatase. It converts certain amounts of testosterone into estradiol (an estrogen). With aging, a man's body will produce larger amounts of aromatase. Larger amounts of aromatase mean more conversion of testosterone to estradiol. This will change the ratio of testosterone to estrogen. A man may have a normal testosterone level, but with an increased estrogen level, the effects of the testosterone are negated. The transformation is not difficult, as the chemical makeup of testosterone and estrogen is very similar.

How Do Levels Of Estrogen Become Elevated?

  • Obesity Studies indicate that obesity is directly related to over-estrogenization in both sexes. All fat cells contain aromatase, so an increase in fat cell population will cause an increase in the conversion of testosterone into estrogen. This will alter the testosterone:estrogen ratios. Obesity is also known to lower testosterone levels at all ages. This may be an excellent reason to trim down and tone up!
  • Zinc Deficiency Zinc inhibits the levels of aromatase in the body. If zinc levels are inadequate, the levels of aromatase rise. Zinc is also necessary for normal pituitary functions. Without zinc, the pituitary gland cannot release the luteinizing and follicle stimulating hormones that stimulate the testes to produce testosterone. An interesting note; while zinc is necessary for testosterone production, testosterone is necessary to maintain levels of zinc in body tissues.
  • Liver Function One of the functions of the liver, is to aid in the elimination of chemicals, hormones, drugs and metabolic waste products from the body. There are a number of factors that will prevent or decrease this from happening. Use of alcohol will diminish liver function. Normal aging will also lessen liver function.
  • Alcohol intake will assist with diminished liver function, and the elimination of excess hormones, drugs and metabolic wastes. Alcohol consumption causes dramatic rises in estrogen levels in the body. Women will have a dramatic rise in their estrogen levels after just one drink. Men will not have a dramatic rise, but levels of estrogen will increase. Heavy drinkers will have high estrogen levels, along with other related symptoms, such as "spider veins", especially on the nose and cheeks, gynecomastia (development of breasts) and testicular atrophy (degeneration or shrinking). Alcohol decreases zinc levels in the body.
  • Prescription Drugs The side effects of some prescription drugs will have a negative effect on the body, and increase the effects of andropause. One example is diuretics (water pills such as Lasix). While necessary to treat conditions such as high blood pressure, the action of the diuretic will diminish levels of zinc in the body. To counteract the effects of the diuretic, a zinc supplement should be taken.

Short-term Effects of Elevated Estrogen in Men

  • Decreased strength
  • Decreased endurance
  • Dermatological changes
  • Decreased libido
  • Decreased sexual performance
  • Dysphoria (restlessness)
  • Fatigue
  • Loss of self-esteem
  • Increased anxiety
  • A decline in physical energy
  • Difficulty in concentration
  • Forgetfulness
  • Insomnia
  • Altered state of well-being

The long-term effects include:

  • Osteoporosis
  • Obesity
  • Erectile dysfunction
  • Muscle loss

Treatments:

  • Lean out!  Fat cells, especially in the abdominal region, produce the aromatase enzyme, which converts testosterone into estrogen. Eliminate alcohol, wheat, commercial dairy, caffeine, soy and any sugars especially in sodas, juices and energy drinks and waters. Only use xyltiol or stevia to sweeten.
  • Reduce or eliminate alcohol consumption to enable your liver to better remove excess estrogens.
  •  Reduce exposure to plastics containing bisphenol A and phtlates.
  • Reduce or eliminate and medications that you are regularly taking that may interfere with your healthy liver function. Common medications include NSAIDs (e.g. ibuprofen, acetaminophen, aspirin), the "statin" class of cholesterol lowering drugs, some heart and blood pressure medications, and some anti-depressants.
  • Increase the amount of cruciferous vegetables such as broccoli, cauliflower, kale these promote the liver to metabolize and excrete excess estrogen. Consider the use of DIM product or Phytogreens formula if you can not eat more of these important vegetables.
  • Optimize vitamin D and essential fatty acid levels.
  • If after six months, the above protocol does not lower excess estradiol levels, then it is recommended that you try the prescription medicine Arimidex (anastrozole), a potent aromatase-inhibiting drug starting at the low dose of 0.5 mg, twice a week increasing to a maximum of 1.0 mg daily. Side effects from this medication is rare.
  • Use 25 mg/day Clomiphene citrate

 

In conclusion: While testosterone is the ‘master’ male hormone if you have too little or too much estrogen, you will never be able to look and feel your best