Are Hunger Hormones Keeping You From Losing Weight?

Leptin and ghrelin are two hormones that have a big impact on how hungry you are and how effectively you lose weight. Learn more about hunger hormones and how to control your hunger!

Every year, millions of people embark on diets, but by the end of the year, the majority of them have regained whatever weight lost and are back to square one. After all, dieting is a difficult task, and it may be even more difficult than you think! Your body has an appetite, and if you eat less calories than you burn on a regular basis, your body responds by increasing your hunger hormones and making you hungry.
 
When it comes to hormones that alter body fat, terms like insulin, testosterone, estrogen, and cortisol are frequently used. Insulin, for example, is frequently cited as a fat-storage hormone and chastised for contributing to weight gain and obesity. While this is simplistic and not totally accurate, two hormones, leptin and ghrelin, may play a far larger and more direct role in weight gain and regulation.
 
These two hunger hormones can have a direct impact on energy balance and play a larger role in weight loss success.
 
Understanding the significance of these two hormones and how to modify them is critical if you want to change your body composition and be successful with long-term weight management.
 
WHAT EXACTLY IS LEPTIN?
 
Leptin, often known as your appetite suppressant, is the main regulator of hunger. Because of its effect on the hypothalamus, a brain region that controls several processes and emotions like hunger, thirst, sleep, and mood, leptin influences food intake.
 
Leptin levels rise when you eat a meal, for example. This sends a signal to your brain, notifying it that your stomach is full and that you should put the fork down. However, if a person is leptin-resistant or the leptin pathway isn't functioning properly, they may continue to overeat and have poor control over their food intake - in other words, they may overeat without realizing it.
 
It's easy to see why leptin is important for long-term dietary adherence and success for these reasons.
 
THE SPIRAL OF LEPTIN
 
Leptin is a hormone that fat cells store and emit. Leptin levels rise when fat mass increases, signaling to your brain to eat less and burn more calories. Conversely, if you reduce your calorie intake and begin to lose body fat, your leptin levels drop, signaling your brain to eat more and burn less! Consider this paradox to be a safety mechanism that keeps energy expenditure and food intake in check.
 
Based on this information, you'd anticipate that someone with excess body fat would have more leptin and, as a result, less food cravings. This sounds fantastic in theory, but research has shown that obese people continue to binge despite increased leptin levels, and their energy expenditure does not increase considerably.
 
This is referred to as leptin resistance. The signal to the brain can become "disrupted" or less "sensitive" when a person acquires weight, causing them to constantly overeat.
 
YOUR LEPTIN LEVELS
 
If you want to lose weight or keep it off, leptin resistance is a major concern. In fact, it's now thought to be one of the most important biochemical reasons of obesity. 5 One obvious strategy to address leptin resistance is to lose body fat, but this requires more than a quick fix diet. Consider the following ways to make a long-term difference and correct leptin resistance:
 
SUBSTITUTE FRUITS AND VEGETABLES FOR JUNK FOOD
 
Excessive inflammation can interfere with leptin's signaling pathway in the hypothalamus. Inflammation may be reduced by eating a mostly unprocessed diet rich in fruits and vegetables, as well as taking specific supplements like omega-3 and antioxidants. 6
 
While cookies and snack cakes may be tasty, they are often less filling than complete foods, are high in calories, and have little nutritional value.
 
MOVE MORE
 
Regular exercise is essential for lowering inflammation and improving leptin resistance. Include resistance and high-intensity interval training in your workouts, which will not only help you control your leptin levels, but will also help you grow muscle and burn fat.
 
EAT MORE PROTEIN
 
Protein may enhance leptin sensitivity as well as help you feel fuller for longer.
 At each meal, aim for 30 grams of lean protein. Chicken breast, white fish, tofu, or lean ground beef are all good options.
 
GET A LOT MORE ZZZZZZZZZZZZZ
 
Aside from the numerous advantages of a good night's sleep, getting eight hours of sleep on a regular basis may also assist enhance leptin sensitivity.
 
8 If you have trouble going asleep, consider any of the following suggestions: Set a regular bedtime, turn off your TV or computer thirty minutes before bedtime, make your bedroom dark, reduce outside noise to a minimum, and set your temperature to around 65 degrees.
 
THE APPETITE GREMLIN, GHRELIN
 
Ghrelin, in contrast to leptin, is an appetite stimulator. It's mostly produced in the stomach, and when levels rise, it sends a hunger signal to the brain, signaling that it's time to eat. Ghrelin levels should return to baseline within three hours after a meal.
 
Ghrelin levels have been demonstrated to be affected by factors such as age, gender, BMI, blood glucose levels, insulin levels, leptin levels, and growth hormone (GH). Ghrelin can be reduced by leptin, for example.
Furthermore, if you frequently feel full after a strenuous workout, it could be due to an increase in GH, which can assist reduce circulating levels of ghrelin, which can help reduce appetite and food consumption.
 
THE HUNGER...
 
Simply said, ghrelin makes you hungry. Why is it so necessary to have a sense of hunger? Because hunger has been identified as a contributing factor in the failure of many diets. 
 
Ghrelin levels have been found to rise after calorie-restricted weight-loss diets in numerous studies. A six-month weight-loss regimen resulted in a 24 percent increase in ghrelin levels, according to a study published in the New England Journal of Medicine. In a more recent study, researchers from the University of Oklahoma saw a 40 percent spike in ghrelin levels after six months of dieting in a male bodybuilder during a six-month prep period! 
 
Your baseline ghrelin levels are likely to be increased if you diet frequently or have dieted multiple times in the past. If you want to stay slender all year or diet again in the future, this could be terrible news.
 
DEFEAT THE GHRELIN GREMLIN
 
While there isn't much research on ghrelin and diet, recent studies have given some light on prospective dietary options that can help you control your hunger and combat the ghrelin gremlin.
Taking roughly 20 grams of oligofructose (a subset of the fiber inulin) per day, split into tiny amounts with each meal, may help lower ghrelin, calorie intake, blood glucose, and insulin levels.
Higher-protein meals, which are well-known for inducing satiety via a variety of pathways, can help lower ghrelin levels.
If you're dieting, sticking to a high-fat, low-carb (ketogenic) diet will help you control your appetite and hunger by lowering ghrelin levels.
Short calorie-cycling diets could be a unique way to manage some of the metabolic adaptations that occur as a result of weight loss. Long-term diets, for example, lowers leptin and raises ghrelin. It may be feasible to offset some of these adaptations by undertaking shorter dieting blocks interspersed with higher-calorie blocks.
 
This is one of the processes that makes weekly high-carb and calorie refeeds so effective. However, refeeding for numerous days in a row is likely to have an effect on ghrelin. 
 
A 4- to 6-week dieting phase followed by a 1- to 2-week caloric maintenance period is a reasonable strategy to calorie cycling. If your maintenance calories are set at 2,700, you'll likely consume approximately 2,200 calories throughout your dieting phase before returning to 2,700 for a few weeks to rest your body.
 
This method may have psychological benefits in addition to supporting leptin and ghrelin levels. When compared to a 12-week (or more) continuous diet, dividing your diet into smaller parts makes it easier to focus and stick to.
 
One of the few studies on the subject to date compared mini-cycles of 11 days of dieting followed by 3 days of maintenance against continuous dieting. Despite having the same total calorie consumption, the group that dieted for 11 days and maintained for three days lost more weight! Surprisingly, these people were able to maintain their weight loss during the maintenance phase.
 
HORMONES OF APPETITE MANAGEMENT
 
Both leptin and ghrelin levels are important for weight loss and dieting effectiveness. Yo-yo dieting is likely to have a negative influence on hormones, body composition, and overall health in the long run.
Plan in periods of energy maintenance or refeeds to avoid the vicious cycle of losing weight and then gaining it back. Smaller durations of 3-4 days every two weeks or longer, or one-week intervals every 4-6 weeks, can be used.
 
While dieting can be difficult, research suggests that maintaining a healthy weight afterward can be even more difficult! Make sure your post-diet strategy is just as good as your diet strategy. Don't skip the gym and aim for 20-30 grams of protein per meal. Exercising is crucial!
 
The tactics outlined above will help you keep your leptin and ghrelin levels in check, but you must plan your diet ahead of time, set clear goals, and be patient with the process. Give yourself plenty of time if you're planning to try cyclical dieting to help your leptin and ghrelin levels.