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Pramipexole
Unlike bromo and Dostinex, Pramipexole is a NON ergot dopamine agonist with high in vitro specificity at the D2 subfamily of dopamine receptors. Pramipexole is a complete agonist and clearly displays a higher affinity to the D3 receptors than to D2 or D4 receptors. While pramipexole displays high affinity for the D2 receptors, it still has low affinity for a2-adrenergic receptors and an untraceable affinity for other dopaminergic, histaminergic, adrenergic, and other receptors. This stuff is POTENT, even though its biggest positive effects on GH are within the first 3 hours after dosing, it still significantly lowers prolactin and for some reason it seems to also have the biggest positive effect on increasing testosterone over all other prolactin blockers. It makes me laugh because the most common feedback you hear about it from someone experiencing it for the first time is the stuffy nose, which is from the increased dopamine which means its working its designated effects.
By Needtogetaas
Unlike bromo and Dostinex, Pramipexole is a NON ergot dopamine agonist with high in vitro specificity at the D2 subfamily of dopamine receptors. Pramipexole is a complete agonist and clearly displays a higher affinity to the D3 receptors than to D2 or D4 receptors. While pramipexole displays high affinity for the D2 receptors, it still has low affinity for a2-adrenergic receptors and an untraceable affinity for other dopaminergic, histaminergic, adrenergic, and other receptors. This stuff is POTENT, even though its biggest positive effects on GH are within the first 3 hours after dosing, it still significantly lowers prolactin and for some reason it seems to also have the biggest positive effect on increasing testosterone over all other prolactin blockers. It makes me laugh because the most common feedback you hear about it from someone experiencing it for the first time is the stuffy nose, which is from the increased dopamine which means its working its designated effects.
By Needtogetaas
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