Tren Cough Explained?

[ODB Senior Member Find all posts View Profile Close ODB]

Created on Sunday, 09 December 2012 14:54
Written by John Connor

I was recently asked "What do you think is the contributing issue with Tren cough immediately after injection? What do you think are some ways to help avoid the issue from surfacing in the first place?"

Over the years I have read various theories from prostaglandin metabolization to pulmonary oil microembolism. I imagine that the causes of "Tren Cough" are varied and it's not always just because of one thing.

I personally have experienced "Tren Cough" on numerous occasions. The symptoms immediately followed a deep IM injection of Trenbolone Acetate. Within seconds after the injection I began having trouble breathing. My airways felt restricted and my eyes began to water from violent coughing that would not relieve the effect. I felt pressure on my chest and had to mentally calm myself during the episode. This violent fit of coughing lasted roughly 2-3 minutes. Towards the end of the episode I felt a bit dizzy or faint. My airways then began to clear and I began to feel relief. It was a scary experience even though I knew about this reaction from reading about it previously. This experience felt life threatening so those who experience it without any prior knowledge must feel very alarmed.

I have noticed that "Tren Cough" seems to happen mostly with the acetate ester and for me personally with higher mg/ml concentrations. I have also noted that "Tren Cough" seems to happen with more frequency when the final product has been converted from Finaplix cattle implants. This may lend support to theories that impurities are a partial cause.

Interestingly, one day I was injecting prescription Testosterone Cypionate into my gluteal muscle IM and I experienced the exact same symptoms as "Tren Cough". The reaction was violent and severe. It was an identical reaction as before. This lends support to the pulmonary oil microembolism theory. I have since had several more minor episodes that were similar but shorter in duration after Testosterone injections.

In 2009 I began experimenting with Subcutaneous (SC) testosterone injections. After I administered a several week course of Testosterone SC I then tried administering Trenbolone acetate subcutaneously. During this next several weeks experiment I had absolutely no "Tren Cough" This may be a suitable method for avoiding "Tren Cough".

SC injections have a slower onset of action in comparison to IM. This slowing of absorption into the blood stream is likely one of the factors that mitigates "Tren Cough" when using this type of injection.


The following abstract offers the pulmonary oil microembolism theory.

Hum Reprod. 1995 Apr;10(4):862-5.
Tolerability of intramuscular injections of testosterone ester in oil vehicle.

Mackey MA, Conway AJ, Handelsman DJ.
Source

Andrology Unit, Royal Prince Alfred Hospital, Sydney NSW, Australia.

Abstract

We undertook a prospective survey of the tolerability of deep i.m. injections of testosterone enanthate in a castor oil vehicle, the most widely used form of androgen replacement therapy. Over a period of 8 months, 26 men received 551 weekly injections into the gluteal, deltoid or thigh muscle and side-effects were recorded immediately and 1 week after each injection by the same nurse using a standardized questionnaire. Most injections caused no complaints [389/551, 70.6% (95% confidence interval 66.6-74.4%)] but minor local side-effects, mostly pain and bleeding, were common [162/551, 29.4% (25.6-33.4%)]; no serious side-effects were observed. Considering all side-effects, the gluteal site had fewer complaints and was less prone to bleeding but was painful more often than deltoid or thigh injection sites. The laterality of injection at any site had no significant effect on side-effects. The only systemic side-effect was episodes of sudden-onset, non-productive cough associated with faintness following eight injections [1.5% (0.6-2.9%)] which we speculate may have been due to pulmonary oil microembolism. We conclude that, when administered by an experienced nurse, deep i.m. injection of testosterone enanthate in a castor oil vehicle is generally safe and well tolerated but causes relatively frequent minor side-effects, including pain and bleeding. An improved depot form of testosterone would be highly desirable for androgen replacement therapy and hormonal male contraception.

PMID: 7650133 [PubMed - indexed for MEDLINE]
http://www.ncbi.nlm.nih.gov/pubmed/7650133

[ds222 Senior Member Find all posts View Profile Close ds222]

only time i got tren cough was when i nicked a blood vessel while injecting

[Bigs251 Senior Member Find all posts View Profile Close Bigs251]

I noticed also the higher dosages I took the more I got it. Worst feeling ever. I was on my hands and knees coughing it was so bad one time

[Mighty49er Senior Member Find all posts View Profile Close Mighty49er]

My first cycle of Tren A, I read somewhere on the boards that if you sipped some water immediately after injecting, you can back off the cough. I tried it and it worked. I felt the cough coming on with the Tren taste and everything but the water or the action of sipping held it at bay. You have to be careful and not cough once or you wont stop. Just a tip for everyone if you didnt know.

[sdmuscle Junior Member Find all posts View Profile Close sdmuscle]

I have been very lucky and not experienced the cough or any other side effects to date. The most I take is 100 MG of the acetate ester every other day or 50 MG daily. I'm a little cautious to try the other longer acting esters, although I'm sure they are fine.

Does anyone know if the Tren produced by most of the known companies is usually a derived from the pellets or are they now made directly in the IM injection?