bolasterone orals

[RonnyT Senior Member Find all posts View Profile Close RonnyT]

As long as we don't have a section to post articles i'll use this forum.

Anabolic steroids can be roughly divided in four groups:

* Testosterone analogues
* C-17 calculated group
* 5-alpha DHT group
* 19-nor group

From the oral steroids (C-17 calculated group) almost everyone knows that they are harsh on the liver. I agree with that, but it?s a little bit to easy.
What about the users individual aspects, such age, health , weight etc. Lets understand that most steroids we use for building muscles and counteracting side-effects are actual medicines meant to treat different medical conditions. If it is prescribed to you by your PhD, it is given to you with a leaflet that also describes the possible side-effects that can arise.

We all know people that take medicines like candy. They pop hands full of painkillers down on a daily basis. The same thing with guys that swallow recreational drugs like by example XTC in numbers. Some people just have no discipline.

Old school bodybuilders where (for the biggest part) health conscious people that trained hard, ate clean, slept well and didn't consume alcohol or cigarettes.
It?s the group of young recreational cosmetic bodybuilders that tend to extremities, they mostly don't want to compete, but want to look impressively big and strong. They love to party and combine AAS with ?speed?- cocaine ? alcohol and smoking cigarettes. They mostly don't eat clean or sleep well. They don't use the AAS as a chemical aid in their cycle, but as means to achieve the looks they so desperately want. I often saw cycles that really scared me. Some of them used insulin and growth hormone together with crazy amounts of steroids, both orals and injectables. This together with their destructive life style will surely lead to health problems sooner or later in their lives. But warning them is useless because they live like there is no tomorrow.
You can try to restrict the sales of alcohol (the USA has tried that before) or marihuana (same ;-)) junk food ( a big part of the world population becomes obese) or steroids, just because a small group of people can't control themselves, but especially this group of people will find ways to obtain the means they want. It is this group of people that also will buy the strongest means available or new compound to try.

Other bodybuilders will also be curious to these heavy compounds like by example metribolone, bolasterone, halotestin etc. Its our responsibility to advise, cq educate them about the safest ways to use these compounds and warn them for the risks involved without turning into a scaremonger.

An article or profile is never complete. You'll find out that these articles will be updated every once and awhile. When we find new or relevant information.

[RonnyT Senior Member Find all posts View Profile Close RonnyT]

An article or profile is never complete. You'll find out that these articles will be updated every once and awhile. When we find new or relevant information.

Bolasterone

Bolasterone belongs to the group of DDR compounds. A group of steroids that where original manufactured in the former DDR (East Germany). These compounds, that a also include Oral Turinabol, have an almost mythical reputation, because through its use the East German athletes where almost unbeatable. While Oral Turinabol is compared with dianabol, bolasterone was compared with oxymetholone, without the fluid retention.
This is not chemical correct, Bolasterone is equal to methyltestosterone with the addition of an extra methyl group at carbon 7. Hence its name dimethyltestosterone. This extra methyl group changes its potency and kinetics tremendously. The same modification (C7-methylation) in chemical structure is also seen in mibolerone (cheque drops) as dimethyl-nandrolone and dimethyltrienolone (dimethyl-trenbolone) which some of you will know to belong to the strongest steroids available. These steroids are all ready very effective in very small doses (micrograms instead of milligrams). This is partly due to the fact that the extra C7-methylgroup makes the compound for the biggest part unable to be bound by bindingproteines like by example SHBG. Which means that most of these stroidmolecules travel free and unbound in the bloadstream to perform their magic on your muscles. The C7-methylation probably also prevents the molecule to be reduced, by the enzyme 5-alpha reductase to a dihydroderivative. An other notorious enzyme, aromatize on the other hand is capable of aromatizing these dimethyl molecules. Later I?ll add some conclusions from a research of Upjohn, the manufacturer of Bolasterone Myagen.

Bolasterone holds the questionable honor of being the first counterfeited brand steroid to hit the international market. A few steroid experts from the United States developed in 1985 a brilliant market strategy. In their articles and columns they where raving it and labeling it as ?the best steroid ever made?. Knowing off course that they would flood the market with their counterfeits.They made 30 ml vials that supposed to contain bolasterone at 10 mg/ml. The counterfeit from the late legendary guru Dan Duchaine contained a mixture from Testosterone cypionate and nandrolone decanoate. Jeff Feliciano sold a mixture from Testosterone cypionate with ground up Anadrol (oxymetholone) in it. One has to understand that the market for raw pharmaceutical ingredients was, in those years, not available for individuals. Thousands of vials where sold for the, especially for the eighties, outrageous price of over 200 dollars. In the spring of 1986 the manufacturers of these drugs where busted. There where several other counterfeiters that followed these famous steroid guru?s, and in their slipstream, sold there own version of Bolasterone.

Due to their methylations these dimethyl compounds are said to be very hepatotoxic (liver toxic), clinical studies found no extra hazard to the user( ). This compound has also a C-17 methylation just like Dianabol and Winstrol. Clinical studies showed that the toxicity on the liver of the C-17 compounds where moderate at least( ). The hepatotoxity is deliberate exaggerated by the official authorities to discourage its use by bodybuilders.
When you use these orals its always better to be safe and stop using re creative drugs, extra medication and alcohol. Liver protectors like silymarin proved to be use full, this is off course also true with excessive alcohol use.

Seen Bolasterone?s potency in the anabolic/androgenic index data, a daily dose in the range from 10-30 mg would be sufficient.

Anabolic steroid-induced hepatotoxicity: Is it overstated?
Clin J Sport Med 1999 Jan;9(1):34-9 (ISSN: 1050-642X)
Dickerman RD; Pertusi RM; Zachariah NY; Dufour DR; McConathy WJ
The Department of Biomedical Science, University of North Texas Health Science Center, Fort Worth 76107-2699, USA.

[RonnyT Senior Member Find all posts View Profile Close RonnyT]

Anabolic Steroids and the Liver

Anabolic steroids are processed by the liver. As discussed earlier, C-17 alkylated oral steroids (steroids with an alkyl group added at the alpha position of the "C-17" or number 17 carbon atom of the molecule to withstand total degradation on their first pass through the liver are unusually harsh on the liver. For this reason, even moderate short-term administration of these C-17 oral steroids can effect liver function test readings. Elevated liver counts indicating liver stress (toxicity) have been reported in recent studies of somewhat moderate oral anabolic steroid therapy (daily doses of 40 and 80 mg of oxandrolone [Oxandrin, formerly Anavar]) as reported in the online periodical Medibolics, edited by Michael Mooney (www.medibolics.com). However, these elevated liver function readings will return to normal after cessation of a moderate, short-term steroid cycle. I could find not one case to the contrary. Further, it is recognized that intense weight training alone often causes changes in liver function tests, including SGOT, SGPT and LDH (this is something that all physicians monitoring athletes using anabolics should be familiar with).

The more serious liver problems attributed to anabolic steroid use include hepatocellular carcinoma (liver cancer) and peliosis hepatitis (blood-filled sacs within the liver). But the majority of cases reporting liver problems have dealt with extremely sick and elderly patients treated with C-17 alkylated oral steroids for years of continuous use, and many of these patients had a particular type of anemia linked to liver tumors even without anabolic steroid therapy. A computer search of the medical literature looking for steroid-associated liver tumors could find only three in athletes (Friedl, 1990). Of the three athletes, one was using 700 mg of oxymetholone a week for five straight years, and one had a tumor more indicative of classic liver cancer than of steroid-associated tumors. Virtually all of the reported liver problems seemed to occur with the 17 alpha-alkylated oral steroids. There have been no cysts or liver tumors reported in athletes using the 17 beta-esterified injectable steroids (Wright & Cowart, p. 61). It has been noted that injectable steroids generally appear to have little effect on the liver at all (Haupt, 1993, p. 469).

Recent studies continue to suggest that reports of serious adverse effects of anabolic steroids upon the liver in healthy athletes may be highly overstated. In a study of athletes, of the 53 current or past steroid users who underwent laboratory testing, only one subject displayed an abnormal liver test (Pope & Katz, 1994, p. 379; incidentally, on physical examination, not one user displayed evidence of any major abnormalities possibly attributable to steroids, such as high blood pressure, edema, acne or hair loss.) Another study tested one of the most powerful and reputedly dangerously toxic anabolic steroids for 30 weeks on HIV positive men and women (Hengge et al.). Oxymetholone, formerly known as Anadrol in the U.S. and a C-17 alkylated oral steroid, was administered in a dosage of over 1,000 mg per week (more than that used by many bodybuilders, and for a much longer duration of uninterrupted use). The results were significant gains in lean muscle mass -- even without any weightlifting. Even more importantly - and surprisingly -- there were no significant problems with liver function, water retention, or virilization side effects (it will be interesting to see whether further studies yield consistent findings at such high dosages).

While the dangers of anabolics to athletes' livers appear to have been highly exaggerated, it must be recognized that an apparently healthy athlete with a previously existing but undiscovered liver problem could do serious damage to himself by self-administering C-17 oral anabolic steroids. For this reason alone, it would be quite irresponsible for any athlete to use anabolic steroids without having a physician regularly conduct blood tests to monitor liver function

[sam1976 Senior Member Find all posts View Profile Close sam1976]

great post, ronny. great information. i especially like the intro. not at all what i had expected. this is much more than the traditional profile that i'm used to seeing.

[GXR64 Senior Member Find all posts View Profile Close GXR64]

Great article, very well put together and full of info.

[strongmann Senior Member Find all posts View Profile Close strongmann]

I heard that Geneeza was making these would be a great product to try!!!!

[RonnyT Senior Member Find all posts View Profile Close RonnyT]

I always tried means and doses (stacks also) when we coached athletes. We also used ourselves as guineapigs. when i worked for WL I didn't wrote about it but I plan to do more reallife hardcore research. Some of my friends will also join. It would be great to use certain steroids (like by example Bolasterone) and compare the results and gains. Side-effects to off course. BigPutte is busy creating new sections. Then we can post content and link them on other forums to this forum to attract more new members.

[Judge Member Find all posts View Profile Close Judge]

Bolasterone oral? must be amazing stuff!

[strongmann Senior Member Find all posts View Profile Close strongmann]

ya judge, blows tbol out of the water!

[Judge Member Find all posts View Profile Close Judge]

is there any company or lab besides Geneza that has put it in production?

[strongmann Senior Member Find all posts View Profile Close strongmann]

nope.. upjohn back in the day were the ones who manufactured this wonder drug!! it was called myagen

[angelo212 Junior Member Find all posts View Profile Close angelo212]

GP Bolasterone
$50.00 USD

Manufacturer: Geneza Pharmaceuticals
Pharmaceutical name: Dimethyltestosterone
Pack: 20 tablets (50mg/tab)

This was a really good thread. This is what brought me over here. I was looking at the lab above and wanted to know more about that compound and came to juicedmuscle. Good info RonnieT.

[RonnyT Senior Member Find all posts View Profile Close RonnyT]

Geneza is marketing and devoloping more rare steroids, new ones wil have to be tested and analysed bc many will want to know quantity/quality is good for sure and good results are no guarantee. wil be continued..;-)