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The oils do have different pharcokinetics, see attachment,, just like the complete solutions, the estrifications, the solvents and co-solvents the viscosity the concentration and the administrationspot. You could use a low viscosity carrier oil like EO or increase the rate by working with mixed compound that uses EO as a co-solvnet at 20%
Abstract
Objective:
In the search for long-acting testosterone preparations suited for substitution therapy of
hypogonadal men, testosterone undecanoate (TU) dissolved in either tea seed oil or castor oil was
investigated.
Design:
* In study I, 1000 mg TU in tea seed oil (125 mg/ml) were injected in equal parts into the gluteal
muscles of seven hypogonadal men.
* In study II, 1000mg TU in castor oil (250 mg/ml) were injected
into one gluteal muscle of 14 patients.
Results:
In comparison with published data on testosterone enanthate, most widely used for i.m.
injections, the kinetic profiles of both TU preparations showed extended half-lives and serum levels not
exceeding the upper limit of normal.
The TU-castor oil preparation had a longer half-life than TU in tea
seed oil 34 vs 21 days
European Journal of Endocrinology 140 414?419
Volume and Concentration
Steroids come in all shapes and sizes. In other words, you can find nandrolone (or Testosterone or boldenone) esters in 25 mg/ml, 50 mg/ml, 100 mg/ml, 200 mg/ml and so forth. Is a 400 mg injection using two milliliters of a 200 mg/ml oily solution the same as using four milliliters of a 100 mg/ml solution? After all, the net amount is still 400 mg, right? Unfortunately, this isn?t the case.
Steroid concentration in the solution greatly affects the dynamics and kinetics. In this study, some of the men received a 100 mg/ml injection of nandrolone decanoate and other men received a 100 mg injection using a 25 mg/ml solution (which means they received four milliliters, of course). Those that received the 100 mg/ml injection reached significantly higher (between 30% and 50%) plasma levels of nandrolone than those who got 100 mg via the 25 mg/ml solution. To top it off, the 100 mg/ml group?s plasma nandrolone level stayed elevated for a little bit longer; however, the length of suppression of endogenous Testosterone was almost identical.
What does this tell us? It tells us that if we want to maximize plasma levels of hormone (and thereby, maximize gains in lean muscle) we want to opt for the most concentrated version of whatever steroid(s) we decide we?re going to use. If we?re using Testosterone, we surely want to use a 200mg/ml enanthate over something like 100mg enanthate. If we?re using nandrolone, we want to use 300mg/ml stuff over 50mg/ml or 100mg/ml nandrolone decanoate made by others.
Injections Sites
Another thing that superficially seems trivial but makes a huge difference in plasma steroid concentrations is where you inject. That?s right, this seems utterly trivial but this study concluded that gluteal injections yielded far superior plasma levels as opposed to injections in the deltoid.
Of all the locations that nandrolone injections were given in this study (100 mg/ml x 1 ml in the glutes, 25 mg/ml x 4 ml in the glutes and 100 mg/ml x 1 ml in the deltoid), the deltoid injections yielded the lowest plasma levels of nandrolone by a huge factor, with peak concentrations being 50% lower than the 100 mg/ml gluteal injection and around 10% lower than the 100 mg/ml x 4ml gluteal injection. Lesson learned here: Only inject in the glutes for maximal steroidal efficacy.
Reference
The Journal of Pharmacology And Experimental Therapeutics, Vol 281, No. 1; 93-102, 1997.
The oils do have different pharcokinetics, see attachment,, just like the complete solutions, the estrifications, the solvents and co-solvents the viscosity the concentration and the administrationspot. You could use a low viscosity carrier oil like EO or increase the rate by working with mixed compound that uses EO as a co-solvnet at 20%
Abstract
Objective:
In the search for long-acting testosterone preparations suited for substitution therapy of
hypogonadal men, testosterone undecanoate (TU) dissolved in either tea seed oil or castor oil was
investigated.
Design:
* In study I, 1000 mg TU in tea seed oil (125 mg/ml) were injected in equal parts into the gluteal
muscles of seven hypogonadal men.
* In study II, 1000mg TU in castor oil (250 mg/ml) were injected
into one gluteal muscle of 14 patients.
Results:
In comparison with published data on testosterone enanthate, most widely used for i.m.
injections, the kinetic profiles of both TU preparations showed extended half-lives and serum levels not
exceeding the upper limit of normal.
The TU-castor oil preparation had a longer half-life than TU in tea
seed oil 34 vs 21 days
European Journal of Endocrinology 140 414?419
Volume and Concentration
Steroids come in all shapes and sizes. In other words, you can find nandrolone (or Testosterone or boldenone) esters in 25 mg/ml, 50 mg/ml, 100 mg/ml, 200 mg/ml and so forth. Is a 400 mg injection using two milliliters of a 200 mg/ml oily solution the same as using four milliliters of a 100 mg/ml solution? After all, the net amount is still 400 mg, right? Unfortunately, this isn?t the case.
Steroid concentration in the solution greatly affects the dynamics and kinetics. In this study, some of the men received a 100 mg/ml injection of nandrolone decanoate and other men received a 100 mg injection using a 25 mg/ml solution (which means they received four milliliters, of course). Those that received the 100 mg/ml injection reached significantly higher (between 30% and 50%) plasma levels of nandrolone than those who got 100 mg via the 25 mg/ml solution. To top it off, the 100 mg/ml group?s plasma nandrolone level stayed elevated for a little bit longer; however, the length of suppression of endogenous Testosterone was almost identical.
What does this tell us? It tells us that if we want to maximize plasma levels of hormone (and thereby, maximize gains in lean muscle) we want to opt for the most concentrated version of whatever steroid(s) we decide we?re going to use. If we?re using Testosterone, we surely want to use a 200mg/ml enanthate over something like 100mg enanthate. If we?re using nandrolone, we want to use 300mg/ml stuff over 50mg/ml or 100mg/ml nandrolone decanoate made by others.
Injections Sites
Another thing that superficially seems trivial but makes a huge difference in plasma steroid concentrations is where you inject. That?s right, this seems utterly trivial but this study concluded that gluteal injections yielded far superior plasma levels as opposed to injections in the deltoid.
Of all the locations that nandrolone injections were given in this study (100 mg/ml x 1 ml in the glutes, 25 mg/ml x 4 ml in the glutes and 100 mg/ml x 1 ml in the deltoid), the deltoid injections yielded the lowest plasma levels of nandrolone by a huge factor, with peak concentrations being 50% lower than the 100 mg/ml gluteal injection and around 10% lower than the 100 mg/ml x 4ml gluteal injection. Lesson learned here: Only inject in the glutes for maximal steroidal efficacy.
Reference
The Journal of Pharmacology And Experimental Therapeutics, Vol 281, No. 1; 93-102, 1997.
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