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Based on the idea that animals form an immobile posture in a non-escapable cylinder filled with water, the forced swim test (FST) is one of the most popular behavioral tests used to evaluate depressive-like behavior in animal models and for the pharmaceutical screening of possible antidepressant treatments. To assess the effectiveness of antidepressant medications and novel substances intended to induce or avoid depressive-like states, Creative Biolabs performs the FST in rodents. Learn more: special forces swim test