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Why casein is actually slower to digest than whey?
From SIBERIANTIGER, 019.05.2012
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Casein is enjoying in bodybuilding because of its slow digestion and make the resulting continuous release of amino acids into the bloodstream, the anti-catabolic casein protein with a long-term effect of an increasing popularity. Even if it is not for the users really are of practical importance to the one or the other might ask, why casein, even if it is present as whey in powder form, over nearly eight hours of amino acid release, during the digestion of whey protein after 3 hours is completed.
The most common explanation
The statement that you read most often in bodybuilding forums, is that casein coagulates in the stomach and forms a thick gel which is digested slowly. This explanation seems by the fact that casein in water, stirred a much firmer consistency than whey protein has to be substantiated. Even in scientific treatises one finds similar statements. In a study that examines the amino acid release from casein and whey protein, it explicitly states, "Indeed, WP is a soluble protein Whereas CAS clots into the stomach, Which delays its gastric emptying and Malthus probably results in a slower release of amino acids." (In fact, there are clumps of WP [whey protein] is a soluble protein whereas CAS [casein] in the stomach, reducing its gastrointestinal residence time increased, probably in a slower release of amino acids) results (1).
The actual explanation
One of the University of Giessen executed study (2) there is a quite different explanation for the comparatively slower rate of digestion of whey from casein. The study's authors attribute the slow rate of digestion of casein contained in beta-casomorphins. In casomorphins are peptides formed during the digestion of casein. These peptides have effects that are similar in some areas where exogenous opioids such as morphine and other opiates. I say "in some areas," as well as poppy seeds, poppy seeds is used for bread and poppy seed cake is to be expected of casomorphins no intoxicating effect. Casomorphins can bind to the opiate receptors in the digestive tract. Since this casomorphins inhibit including the Darmpersistaltik (voluntary self-mobility of the intestine), the rate of digestion is reduced.
This thesis is demonstrated in the aforementioned study using two simple experiments. In the first experiment the test animals for opiate receptor antagonist naloxone was given the name, which blocks the opiate receptors in the digestive tract. When the opiate receptors were blocked, casein showed almost the same speed as whey protein digestion, and the differences in gastric emptying rate were partially offset with respect to intestinal transit time in full. This could be shown that the coagulation or clotting of casein in the stomach is not the primary reason for the slower rate of digestion, but can at most contribute in part to the longer gastric residence time.
As a blank whey protein with the casomorphins D-Ala-beta-casomorphin-4 and mixed D-Ala-beta-casomorphin-5 and administered to test animals. It was found that the intestinal transit time of whey protein levels being dose-dependent with the Casomorphinmenge.
What impact does this have on the rate of digestion of multi-component proteins, which in addition to casein and whey digest quickly?
This explanation also has practical implications for the rate of digestion of multi-component proteins that contain both fast and slow digestible digestible whey protein casein. Often these products are advertised so that they combine because of the whey protein contained the amino acid rapid release of whey protein with the slow release of amino acid casein.
This is not exactly true, since the digestion is slowed by the whey protein contained in the digestion of casein resulting casomorphins. While it is not assumed that the entire protein mixture which due to the contained casein protein the same rate of digestion and amino acid release rate as pure casein, but it is assumed that the rate of digestion and amino acid release rate of the contained whey and other contained proteins to some extent in the direction of a slower digestion can be changed.
The degree of this change is related to the protein contained in the multicomponent Kaseinmenge and the therefrom resulting in digestion amounts of casomorphins in combination, wherein the digestion is slowed even more stronger the higher the precipitates casein. In other words, in multi-component proteins contained in whey with casein digests slower than whey protein alone using.
References:
Yves Boirie, Martial Dangin, Gachon Pierre, Marie-Paule Vasson, Jean-Louis Maubois, and Bernard Beaufrère. Slow and fast dietary proteins differently modulate postprandial protein accretion. Proceedings of the National Academy of Sciences of the United States of America, 1997, Issue 94, Page 14930-14935
Daniel, H., Vohwinkel, M. & Rehner, G. Effect of casein and beta-casomorphins on gastrointestinal motility in rats. The Journal of Nutrition, 1990, issue 120 Number 3, Page: 252-7
Why casein is actually slower to digest than whey?
From SIBERIANTIGER, 019.05.2012
Send this Print Discussion
Casein is enjoying in bodybuilding because of its slow digestion and make the resulting continuous release of amino acids into the bloodstream, the anti-catabolic casein protein with a long-term effect of an increasing popularity. Even if it is not for the users really are of practical importance to the one or the other might ask, why casein, even if it is present as whey in powder form, over nearly eight hours of amino acid release, during the digestion of whey protein after 3 hours is completed.
The most common explanation
The statement that you read most often in bodybuilding forums, is that casein coagulates in the stomach and forms a thick gel which is digested slowly. This explanation seems by the fact that casein in water, stirred a much firmer consistency than whey protein has to be substantiated. Even in scientific treatises one finds similar statements. In a study that examines the amino acid release from casein and whey protein, it explicitly states, "Indeed, WP is a soluble protein Whereas CAS clots into the stomach, Which delays its gastric emptying and Malthus probably results in a slower release of amino acids." (In fact, there are clumps of WP [whey protein] is a soluble protein whereas CAS [casein] in the stomach, reducing its gastrointestinal residence time increased, probably in a slower release of amino acids) results (1).
The actual explanation
One of the University of Giessen executed study (2) there is a quite different explanation for the comparatively slower rate of digestion of whey from casein. The study's authors attribute the slow rate of digestion of casein contained in beta-casomorphins. In casomorphins are peptides formed during the digestion of casein. These peptides have effects that are similar in some areas where exogenous opioids such as morphine and other opiates. I say "in some areas," as well as poppy seeds, poppy seeds is used for bread and poppy seed cake is to be expected of casomorphins no intoxicating effect. Casomorphins can bind to the opiate receptors in the digestive tract. Since this casomorphins inhibit including the Darmpersistaltik (voluntary self-mobility of the intestine), the rate of digestion is reduced.
This thesis is demonstrated in the aforementioned study using two simple experiments. In the first experiment the test animals for opiate receptor antagonist naloxone was given the name, which blocks the opiate receptors in the digestive tract. When the opiate receptors were blocked, casein showed almost the same speed as whey protein digestion, and the differences in gastric emptying rate were partially offset with respect to intestinal transit time in full. This could be shown that the coagulation or clotting of casein in the stomach is not the primary reason for the slower rate of digestion, but can at most contribute in part to the longer gastric residence time.
As a blank whey protein with the casomorphins D-Ala-beta-casomorphin-4 and mixed D-Ala-beta-casomorphin-5 and administered to test animals. It was found that the intestinal transit time of whey protein levels being dose-dependent with the Casomorphinmenge.
What impact does this have on the rate of digestion of multi-component proteins, which in addition to casein and whey digest quickly?
This explanation also has practical implications for the rate of digestion of multi-component proteins that contain both fast and slow digestible digestible whey protein casein. Often these products are advertised so that they combine because of the whey protein contained the amino acid rapid release of whey protein with the slow release of amino acid casein.
This is not exactly true, since the digestion is slowed by the whey protein contained in the digestion of casein resulting casomorphins. While it is not assumed that the entire protein mixture which due to the contained casein protein the same rate of digestion and amino acid release rate as pure casein, but it is assumed that the rate of digestion and amino acid release rate of the contained whey and other contained proteins to some extent in the direction of a slower digestion can be changed.
The degree of this change is related to the protein contained in the multicomponent Kaseinmenge and the therefrom resulting in digestion amounts of casomorphins in combination, wherein the digestion is slowed even more stronger the higher the precipitates casein. In other words, in multi-component proteins contained in whey with casein digests slower than whey protein alone using.
References:
Yves Boirie, Martial Dangin, Gachon Pierre, Marie-Paule Vasson, Jean-Louis Maubois, and Bernard Beaufrère. Slow and fast dietary proteins differently modulate postprandial protein accretion. Proceedings of the National Academy of Sciences of the United States of America, 1997, Issue 94, Page 14930-14935
Daniel, H., Vohwinkel, M. & Rehner, G. Effect of casein and beta-casomorphins on gastrointestinal motility in rats. The Journal of Nutrition, 1990, issue 120 Number 3, Page: 252-7
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