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F.I.S.T.
05-01-2011, 06:33 PM
Proviron

(Mesterolone)
[1 alpha-methyl-17 beta-hydroxy-5 alpha-androstan-3-one]
Molecular Weight: 304.4716
Molecular Formula: C20H32O2
Melting Point: N/A
Manufacturer: Schering
Release Date: 1960
Effective Dose: 25-200mgs/day
Active Life: up to 12 hours
Detection Time: 5-6weeks
Androgenic: Anabolic Ratio:30-40/100-150

Proviron (mesterolone) is basically an orally active DHT (Dihydrotestosterone) preparation. For comparision, we can think of some other orally prepared DHT compounds like Winstrol, Anavar, etc? Those both act very similarly in mechanism to Proviron, but a more accurate way to think of this compound is as something like ?Oral Masteron.? As I?m sure you noticed, their anabolic/androgenic ratio is very similar.Remember, DHT is 3 to 4 times as androgenic as testosterone and is, of course, incapable of forming estrogen. Also, Proviron is quite unique in that a simple look at it?s 4-ring structure will show us that it is not going to be too liver toxic, since it is not c17-Alpha-Alkylated, as many orals are?this modification (lacking in Proviron) makes drugs more liver toxic. Proviron has a 1-metyhl group added, instead. Looks pretty great on paper, right? Well, as usual, things tend to look better on paper than they do in the body. Your body has a negative feedback loop which prevents your body from having too much DHT floating around(if you?ve been paying attention up to now from reading my other stuff, you already know this). An excess of DHT will eventually be changed into another (largely not anabolic) compound.

And of course, being a DHT-based compound, this stuff isn't going to be great for female athletes to use. Virilization (development of male sexual characteristics) is going to be a concern for women daring enough to try this stuff. My advice is that there is much better, safer compounds for female athletes and bodybuilders to use.

F.I.S.T.
05-01-2011, 06:34 PM
So lets go back to the comparison with being some sort of “Oral Masteron”…basically since Proviron is 5-alpha reduced and not capable of forming estrogen, and also has a very high affinity for binding to the aromatase enzyme (the enzyme responsible for converting all that good testosterone in your body into all that nasty estrogen). That means if you choose to take proviron with testosterone (and I know you wouldn’t even be doing a cycle without including some form of testosterone) and/or any aromatizable steroid, it should actually serve to prevent estrogen build up by the aforementioned binding to the aromatase enzyme, which prevents aromatase from doing it’s dirty work and making a bunch of estrogen out of the other steroids you are taking. It should also be noted that Proviron also binds very well to SHBG (Sex Hormone Binding Globulin…a hormone responsible for reducing the amount of circulating free testosterone in your body)(1). As a matter of fact, in the last study I read, it bound to SHBG better than any other drug studied. Also, I’d like to note that Proviron bound to the Anabolic Receptor better than any oral anabolic (except for the insanely toxic MethylTrienolone), having an ability to bind to the AR better then testosterone, but not as well as Nandrolone (1). Unfortunately, as we know, DHT also has a high affinity for binding to receptors in the scalp and prostate, causing some possible nasty side effects, like male pattern baldness and prostate enlargement. It’s important to remember that DHT and DHT derived compounds are used quite successfully to treat gynocomastia, and in this area, Proviron is no different.

Lets delve into some of the positive points of this drug before we go any farther. Androgen Receptors are found in fat cells as well as muscle cells(5), and whilethey act on the AR in muscle cells to promote growth, they also act directly on the AR in fat cells to affect fat burning.(9)(3) The stronger the androgen binds to the A.R, the higher the lipolytic (fat burning) effect on adipose (fat)tissue(6)(2). As if that’s not enough good news, some steroids (notably, testosterone) even increase the numbers of A.R. in muscle and fat (9)(7). Thus, if you are taking a simple stack of proviron and testosterone, you’ll have more of the test you shoot as free testosterone floating around building muscle (compliments of the Proviron), more androgen receptors to be bound to (compliments of your testosterone) by your Proviron, thus causing more fat loss. Testosterone and Proviron are a very nice synergistic stack, pretty nearly an “ideal” stack of an oral and injectable, because both drugs will actually act to enhance the effect of the other.

F.I.S.T.
05-01-2011, 06:34 PM
So what we have here is a steroid which can basically make other steroids more effective by preventing their conversion into estrogen, as well as increasing the amount of circulating free testosterone in your body. This of course all provides a more hardened and quality look to muscles. Proviron is very much a “synergistic” drug in this respect, and it’s inclusion in any cycle would definitely make all of the other steroids perform better, and provide better gains. This is all compounded by the fact that proviron is a very lipolytic (fat-burning) drug.

Now, as if all of this weren’t enough, lets talk about how Proviron affects your HPTA (Hypothalamic-Pituitary-Testicular-Axis)…the thing that regulates the male hormonal system. When a reasonable dose of this stuff is given (100-150mgs/day), it had no depressing effect on low or normal serum FSH and LH levels (6). Follicle Stimulating Hormone (FSH) and Leutenizing Hormone (LH) are two hormones which send a signal to your testes to produce testosterone. Good news for people considering it for PCT is that it can even raise your LH (10)! Thus, by not suppressing those hormones and maybe even raising some, your normal testosterone levels will remain intact. This points to a novel use for this compound during Post-Cycyle-Therapy for a non-suppressive “bridge” between cycles. In fact, in yet another study, administration of Proviron (basically the same dose as in the last study) produced no changes in steroids, thyroid hormones, gonadotropins nor PRL (Prolactin Levels…you want those to remain low).(8).

Unfortunately, this stuff is not too hot on it’s own. It’s a good drug for inclusion in a cycle containing testosterone and other armoatizable steroids, and it’s a good drug for a possible “bridge” between cycles. Alone, however, as an androgenic or anabolic agent, it’s effects have been very weak in both studies (9), as well as in the experience of everyone I spoke to about it. This may be due to the addition of the 1-methyl-group to DHT, which makes this stuff orally active. Whatever the case, as a stand alone anabolic or androgenic compound, it’s not too impressive.

graffix
05-01-2011, 09:51 PM
I personally like proviron, keeps my muscles as hard as my johnson

Dbolli
05-01-2011, 10:59 PM
I personally like proviron, keeps my muscles as hard as my johnson

LMAO. I love proviron. I just always get NRBs (no reason boners) in the most un-called for moments.

graffix
05-02-2011, 01:47 AM
Right on bro.... like church or something lol

Bush
05-02-2011, 03:53 PM
I think Proviron is an oral anabolic steroid of the generic compound mesterolone , but behaves as an anti-aromatase agent Thus, Proviron is classified as an androgenic steroid and anti-aromatization prescription drug. Proviron is considered a weak anabolic, it is more popular for its ability to prevent gyno and fluid retention.

Cage fighter
05-03-2011, 01:19 AM
How much do you take a day?

kodak_flash
05-05-2011, 07:40 PM
will it help with a cutting stack or dieting?

RedDragon
05-05-2011, 08:05 PM
will it help with a cutting stack or dieting?for sure...
and personally i use it also when im off cycle,low dosage,for 6-8 week just to keep muscle hard and vascular;also sex drive is improved.

dboss10
05-08-2011, 11:59 PM
Ill be running this stuff in my next cycle for sure. I hear the sex is amazing lol. Thats what im talkin about:)

dboss10
05-09-2011, 12:00 AM
Right on bro.... like church or something lol

Lmao. Thats hilarious. Dude where do you come up with these avitars? Str8 comedy

capo
05-15-2011, 09:19 AM
for sure...
and personally i use it also when im off cycle,low dosage,for 6-8 week just to keep muscle hard and vascular;also sex drive is improved.

could you use this straight after an oral cycle to try and hold onto gains ,on pct/keep running for another 4 weeks after pct

Cage fighter
05-16-2011, 03:14 PM
I want to use this in my next cycle with test and deca
1-5Anadrol 50
1-14Test 800mgs a week
1-10Deca 400mgs a week
Should I run the proviron threw the whole cycle at 50 mgs a day?

F.I.S.T.
05-16-2011, 10:08 PM
I want to use this in my next cycle with test and deca
1-5Anadrol 50
1-14Test 800mgs a week
1-10Deca 400mgs a week
Should I run the proviron threw the whole cycle at 50 mgs a day?

Yes,you can run it the entire cycle.50mg is quite low though.Prov is prescribed at 100-150mg ed so I would at least go with 100mg and see how works and adjust the doseage accordingly.

F.I.S.T.
05-16-2011, 10:10 PM
could you use this straight after an oral cycle to try and hold onto gains ,on pct/keep running for another 4 weeks after pct

Many guys have used Prov as a bridge between cycles to help hold onto their gains and have had great success with it.A lower dose of say 50-75mg ed will make a good bridge until your next cycle.

PowerSergNY
03-05-2012, 04:11 AM
I read up on Proviron, has anyone notice hair loss?
Thanks?

F.I.S.T.
03-13-2012, 04:33 PM
I read up on Proviron, has anyone notice hair loss?
Thanks?

Never had an issue with it but I am not prone to it anyway so im not a fair judge.

bill2011
03-13-2012, 09:59 PM
I just order 4 pack for the bridge what you think about this
Length 12 weeks
Weeks 1-4 GP Methan10 40 mg per day(1week on the 12 week begin)
Weeks 1-12 500mg GP Test Cyp (per week 1ml Mon an 1ml Thur)
Weeks 1-12 GP Anastrozole .5 mg EOD (continue to run this for 10 days after cycle)


PCT
Week 10-16 50mg GP Proviron per day
Week 14-20 50mg GP Clomiphene per day
Week 16-22 20mg GP Nolva
Don’t be afraid to PCT for long time!!!!!

bill2011
03-13-2012, 10:15 PM
Or 8-14 50mg GP Proviron per day

Liquid
03-21-2012, 09:23 AM
Many guys have used Prov as a bridge between cycles to help hold onto their gains and have had great success with it.A lower dose of say 50-75mg ed will make a good bridge until your next cycle.

Very nice addition during or as a bridge to any cycle!

allergate
04-30-2012, 09:19 PM
Im just using 25mg per day of this and just started a test/tren cut and my nuts are a swinging low lol - love proviron lol :)

Krazy
05-01-2012, 01:53 AM
I could be wrong, but I don''t think so... Proviron has a direct metabolic pathway into DHT? DHT is well known to cause hair loss in men that are prone to it. I have taken both Proviron and Masteron and neither caused me to have any hair loss.

BeauBody38
01-10-2015, 03:56 AM
Warnings
The British pharmaceutical website Net Doctor reports that Proviron should not be used by patients with pre-existing liver tumors. As Proviron can enlarge the prostate, elderly men or men with pre-existing prostate cancer should also avoid using Proviron.

Bayer additionally reports that patients with hypercalcemia (high blood levels of calcium) should not take Proviron, and that before taking Proviron, patients with high blood pressure, diabetes, kidney disease, epilepsy or heart disease should consult with a physician to discuss risks and complications to these conditions that Proviron might cause.

Children, women who are pregnant or women who could become pregnant should avoid using this drug. Drugs.com states that androgens given to pregnant women have caused female fetuses to develop masculine feature, and that externally administered androgens may stunt the growth of children.

beatricia2
05-28-2015, 03:55 PM
before easy to buy in italie now impossible, good product before training. but underground lab are really put proviron on tabs???

F.I.S.T.
07-10-2015, 12:15 AM
bump to the top.

franck
07-10-2015, 12:38 PM
Not so impossibile to find,beatricia. .underground and official Brand not too expensive. .

beatricia2
07-19-2015, 07:16 AM
ok franck happy to see that.

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for libido proviron is number one, for cutting aslo very good.