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RonnyT
03-09-2011, 05:52 PM
Do we have home brewers cq kitchenbrewers on our forum? Anyone tried to make complexes in tabletform or sublingual drops? At the moment I'm experimentin with Cialis and Vardenafil. They are the most easy compounds to check if it works okay. Either you get hard on or you don't. You know within the hour. If you complex a dteroid it takes longer :o


The best tool available to make nasal and sublingual steroids are derivatives of beta cyclodextrins. The one that is most readily available is hydroxypropyl-beta cyclodextrin (HPBCD). (Note: Plain beta-cyclodextrin is of little use) In case you have not heard of these, cyclodextrins are cyclic oligosaccarides (sugars) that have a hydrophilic outer surface and a hydrophobic inner surface.(3) They can be thought of as a doughnut, with the centre capable of having a steroid molecule stuck inside it. The hydrophilic outer surface makes the cyclodextrin soluble in water, and when it is combined with a steroid, it can make the poorly water soluble steroid soluble as well.(3) In addition to making steroids soluble, cyclodextrins have very other important properties that make them ideal for our purpose. Cyclodextrins are known to enhance steroid delivery through biological membranes.(3) The large CDs themselves are very bad at permeating biological membranes, but they deliver the steroid to the membrane, where it partitions into the membrane, leaving the CD on the outside of the membrane.(3) The conventional penetration enhancers like alcohols or polyethylene glycol act by disrupting the lipid layers of membranes.(3) That is a big source of irritation from the old formula, and this irritation can thus be avoided by the use of CD?s. Another advantage is, once administered, the steroid is rapidly absorbed. Nearly 95% of the steroid will be absorbed within 20 minutes. This also causes the need for multiple doses throughout the day.

RonnyT
03-09-2011, 05:58 PM
If there is any interest in this subject I'll post some more information

AwesomeSmiley
03-09-2011, 06:11 PM
Lol you're like some crazy chemist teacher I had back in the school days. This goes way over my head, but I do find it interesting. I just stick to maths :(

dino
03-10-2011, 05:22 AM
CD are like a donut right? You can just mix together CD and a drug(AAS or Cialis-Viagra) or it's more complex? The drug "go in the hole of the CD" just mixing the 2 compounds?

dino
03-10-2011, 05:24 AM
Maybe a "Chemical warriors" subforum could be appreciated...i love to read article about homebrewing and to see photos of these magic kitchen:)?

RonnyT
03-10-2011, 10:16 AM
CD are like a donut right? You can just mix together CD and a drug(AAS or Cialis-Viagra) or it's more complex? The drug "go in the hole of the CD" just mixing the 2 compounds? Yep and then the CD's push the drug through your mucous membranes (underneath the tongue and inside cheek) into the system, without the fist pass through the liver. Thats why it works very quick (its used with medication at a heartattack) and has a high deliverypercentage. Its also usefull to deliver compounds like halotestin that are harsh on the liver.

limo
03-18-2011, 07:16 PM
If you need any guinea pigs for this stuff give me a shout...would love some home cooked stuff

player
03-19-2011, 06:23 AM
honestly? sounds very good

Judge
03-19-2011, 09:28 AM
If you need any guinea pigs for this stuff give me a shout...would love some home cooked stuff
THAT ;) Ι am always available to be a tester Ronny

manu
03-20-2011, 05:37 PM
Hi everybody, I tried 2 years ago to make transdermal test base.
I bought 10g of test base, and Phlogel.
Unfortunately I didn't really notice any effect, even at 200mg / days ... according 20% assimilation, this leaved me with 40mg / day into bloodstream, so 280 of pure test / week.
Didn't need a pct.
Some month after, I had my first cycle, and with 250mg test enanthate / 5 days for 10 weeks, I gained 20 lbs. The diet and training were the same.
We have to remember that this leaved me with about 180mg of pure test into the bloodstream ( due tu the weight of ester, but I don't really remember the real value ).

So there are 2 possibilities :
1 ) I didn't compounded well my gel, but I don't think because I dissolved first my test with minimal ethanol, and then added to my phlogel, and the concentration was low.
whatsmore, I had no residues left in my skin after application.
2 ) My test base powder was fake / or contained other ingr?dients ...

then I read with HPBCD, and wanted to try but was unable to find a source ...
So if someone know where to find it, I will be happy to test with tren powder ( from fina )
Please Ronny keep us informed with your experiences ;)

RonnyT
03-22-2011, 06:37 AM
I tried phlogel too, but I liked DMSO better.

After 24 hours stirring the cyclodextrines, the Cialis (tadalafil) is a suspension and Vardenafil is a clear solution.
Vardenafil is much better en stronger thus thats no problem.

Judge
03-22-2011, 02:20 PM
I tried phlogel too, but I liked DMSO better.

After 24 hours stirring the cyclodextrines, the Cialis (tadalafil) is a suspension and Vardenafil is a clear solution.
Vardenafil is much better en stronger thus thats no problem.
interesting compounds Ronny, have you tried yourself? feedback on them?

goanywhere
03-22-2011, 03:39 PM
If I may - let me extend my sincere and eager offer to help you test your brew. For scientific purposes only of course.


interesting compounds Ronny, have you tried yourself? feedback on them?

Yes Judge - it is interesting.

Ronny - I hope the results are even better than you expected or hoped for.

RonnyT
03-26-2011, 06:41 AM
Its for a client and I'm still experimenting. This time the API is strong, if you put some powder underneath your tongue and let it dissolve you walk around with a boner for a few days. Tadalafil powder is just a little chalky and tasteless. Vardenafil is bitter as hell. A friend of mine will test it in arteficial liqued sugar.

I made CD tabs in the past and then the API wasn't good. It turned out to be Mibolerone instead of Fluoxymesterone.

Judge
03-26-2011, 09:09 AM
if you put some powder underneath your tongue and let it dissolve you walk around with a boner for a few days..

I like this part ;)

goanywhere
03-26-2011, 12:16 PM
I like this part ;)

Laughing. That caught my attention too. It does sound very damn interesting.

Ronny - I don't know how you can spend all that time and effort - and not try it. Your a good man!

RonnyT
03-26-2011, 02:03 PM
I'm experimenting for clients and of course i know where I'm talking about. But if I spent all my time fucking around I have no time left to write experiment etc. Pt 141 by the way is GREAT!! You'll need to inject it and it has some sides, but the effects are beyond believe. Some of my friends swear by it. Lotta companies have tried to alter the sides and application by example a nasal spray, but the only way is to inject and timing - eating etc come precise, but when you do it right..;) .. and it works for girls also just like GHB.

goanywhere
03-26-2011, 09:27 PM
Ronny that is very impressive.

Let me know if Naps ever carries anything you were involved with.

Would be great fun to try.

goanywhere
03-26-2011, 10:14 PM
By the way Ronny - any special place or rules for the injection? Just wondering.

RonnyT
04-01-2011, 09:35 AM
One of the guys testing this with his girlfriend mailed me this (I translated).

141 pt
usage: add 2 ml of water to the vial
The first injection shoot 1iu (sub-q), no more or you will be sick
after the first injection, the 2 to 4 hours before it starts to work
after half hour you will become little sick:) later you’ll have less trouble
I think your body must first convert this stuff
in normal use 2 iu is enough for 2 days of fun
for women it is better to stick to1 iu, because women are more prone to the
the nauseating feeling .
sides: you'll become a tan or get redish, you can also get stains
on your body (I also became some oops) ..
a disadvantage is, if you've used PT 141 a few times, there is craving for more, because the sex is just many
better as normal,
a downside is that it is almost impossible to buy the real deal, and your dick gets so hard that if you want to
urinate or ejaculate it is almost impossible, but fortunately you are so horny you just keep on going

nice article : http://nymag.com/lifestyle/sex/annual/2005/15061/

goanywhere
04-01-2011, 02:46 PM
Ronny - thank you very much!

It sounds very interesting. Do you know what is considered to be an "iu" with PT-141?

A few days ago - I was searching for PT141 and only found dubious sources. Then I found it - on N--s!

Once again - thank you!